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加味竹叶石膏汤治疗急性痛风性关节炎临床研究 被引量:25

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摘要 目的:探讨加味竹叶石膏汤治疗急性痛风性关节炎临床疗效。方法:采用随机、对照的临床研究设计方案,收集80例湿热蕴结证急性痛风性关节炎患者,按随机法分为治疗组和对照组各40例,其中治疗组予加味竹叶石膏汤,对照组予塞来昔布胶囊。结果:经过14天治疗后,两组均能有效改善临床症状和中医证候积分,临床疗效和证候疗效的总有效率相似(P>0.05),对ESR、CRP、IL-1等炎性指标两组均明显改善(P<0.05);在降低血尿酸水平方面,治疗组下降明显,优于对照组(P<0.05)。结论:加味竹叶石膏汤能有效改善急性痛风性关节炎临床症状,控制病情,降低血尿酸及炎性指标,且安全性较好。
出处 《浙江中医杂志》 2012年第3期177-179,共3页 Zhejiang Journal of Traditional Chinese Medicine
基金 云南省应用基础研究计划项目竹叶石膏汤介导IL-1b信号通路抑制痛风性关节炎的机制研究 编号:2011FZ262
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