摘要
目的 观察男性乙型肝炎表面抗原(HBsAg) 阳性患者血清雌二醇(E2) 和睾酮(T) 水平的变化。方法 采用放射免疫分析法对135 例男性HBsAg 阳性患者(阳性组)和107 例年龄匹配的男性HBsAg 阴性者( 阴性对照组)血清E2 和T水平进行测量。结果 男性HBsAg 阳性患者4 个年龄组(20~29,~39,~49 ,~70 岁) 血清E2 水平明显高于年龄匹配的阴性对照组( P<0-01) ,而血清T水平明显低于年龄匹配的阴性对照组( P< 0-01) 。结论 男性HBsAg 阳性患者血清E2 水平增高,而血清T水平降低。
Objective To evaluate the changes in serum estradiol (E 2) and testosterone (T) levels in male patients with positive HBsAg.Methods Serum E 2, T and HBsAg were measured by using radioimmunoassay in 135 male patients with positive HBsAg (patient group) and 107 age-matched male normal subjects (control group).Results Serum E 2 concentrations were significantly higher and serum T levels were lower in patients with different age (20~29) years, ~39 years, ~49 years and ~70 years) than those of age-matched contrl group ( P <0 01).Conclusion There is an increase of serum E 2 levels and a decrease serum T levels in male patients with positive HBsAg.
出处
《广东医学》
CAS
CSCD
2000年第1期20-21,共2页
Guangdong Medical Journal