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尿毒症血透患者EPO不同给药方法的疗效比较

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摘要 目的分析EPO不同给药方法对尿毒症血透患者的疗效。方法根据治疗前甲状旁腺素(PTH)水平将88例尿毒症患者分为2组:高PTH组28例,正常PTH组60例。每组再随机分为2组:一组(A组)应用EPO2 000U皮下注射,每周3次;另一组(B组)应用EPO 6 000U皮下注射,每周1次。高PTH组另加口服罗钙全。每组治疗前与治疗后进行PTH、Hb、Hct、SBP检测。结果各组患者治疗前后比较:Hb、Hct较前升高,差异有统计学意义(P<0.05),高PTH组治疗前后比较,PTH差异有统计学意义(P<0.05);与分次给药组(A组)比较,单次给药组(B组)中SBP均明显升高,差异有统计学意义(P<0.05)。PTH与Hb、Hct均呈负相关(r=-0.652,P<0.01;r=-0.518,P<0.01)。结论 EPO分次给药效果优于一次给药的效果。
出处 《实用临床医学(江西)》 CAS 2012年第2期46-47,共2页 Practical Clinical Medicine
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