期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

弥漫性轴索损伤预后相关因素研究进展 被引量：8

下载PDF
导出
摘要 弥漫性轴索损伤（diffuse axonal injury，DAI）是一种以神经元轴索肿胀、断裂和轴索球形成为主要病理特征的特殊类型颅脑损伤。DAI导致患者严重的神经功能缺陷和神经心理学障碍，但目前对DAI仍缺乏特异性治疗措施^[1]。因此，对DAI预后影响因素进行分析显得尤为重要。
作者 尹义国 李甲 冯东福
机构地区 上海交通大学医学院附属第三人民医院神经外科
出处 《中华神经外科疾病研究杂志》 CAS 2012年第2期181-183,共3页 Chinese Journal of Neurosurgical Disease Research
基金 上海市卫生局科研基金资助项目(2010167) 上海交通大学医工合作专项基金资助项目(YG08PETMS19)
关键词 弥漫性轴索损伤 预后
分类号 R651.15 [医药卫生—外科学]
  • 相关文献

参考文献25

  • 1顾磊,冯东福,朱志安.弥漫性轴索损伤的特异性药物治疗进展[J].中国临床神经外科杂志,2009,14(10):635-637. 被引量：9
  • 2Schaefer PW,Huisman TA,Sorensen AG,et al.Diffusion-weightedMR imaging in closed head injury:high correlation with initial glasgowcoma scale score and score on modified Rankin scale at discharge[J].Radiology,2004,233(1):58-66.
  • 3Tong KA,Ashwal S,Holshouser BA,et al.Diffuse axonal injury inchildren:clinical correlation with hemorrhagic lesions[J].Ann Nerol,2004,56(1):36-50.
  • 4Babikian T,Freier MC,Tong KA,et al.Susceptibility weightedimaging:neuropsychologic outcome and pediatric head injury[J].Pediatr Neurol,2005,33(3):184-194.
  • 5Paterakis K,Karantanas AH,Komnos A,et al.Outcome of patientswith diffuse axonal injury:the significance and prognostic value of MRIin the acute phase[J].J Trauma,2000,49(6):1071-1075.
  • 6Marquez de la Plata C,Ardelean A,Koovakkattu D,et al.Magneticresonance imaging of diffuse axonal injury:quantitative assessment ofwhite matter lesion volume[J].J Neurotrauma,2007,24(4):591-598.
  • 7Zheng WB,Liu GR,Li LP,et al.Prediction of recovery from a post-traumatic coma state by diffusion-weighted imaging(DWI)in patientswith diffuse axonal injury[J].Neuroradiology,2007,49(3):271-279.
  • 8Li J,Li XY,Feng DF,et al.Quantitative evaluation of microscopicinjury with diffusion tensor imaging in a rat model of diffuse axonalinjury[J].Eur J Neurosci,2011,33(5):933-945.
  • 9Huisman TA,Schwamm LH,Schaefer PW,et al.Diffusion tensorimaging as potential biomarker of white matter injury in diffuse axonalinjury[J].AJNR Am J Neuroradiol,2004,25(3):370-376.
  • 10顾磊,李甲,冯东福,李建奇,王博成,朱志安.弥漫性轴索损伤后早期磁共振弥散张量成像与工作记忆障碍的相关性研究[J].中国临床神经外科杂志,2011,16(5):270-273. 被引量：5

二级参考文献62

  • 1王恩任,程永忠,毛伯鏞,何泽友,邱胜春.创伤性脑弥漫性轴索损伤106例[J].中华创伤杂志,2004,20(8):499-500. 被引量：4
  • 2Li XY, Feng DF. Diffuse axonal injury: novel insights into detection and treatment [J]. J Clin Neurosci, 2009, 16(5): 614 - 619.
  • 3Buki A, Farkas O, Doczi T, et al. Preinjury administration of the calpain inhibitor MDL-28170 attenuates traumatically induced axonal injury [J]. J Neurotrauma, 2003, 20(3): 261 - 268.
  • 4Ai J, Liu E, Wang J, et al . Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury [J]. J Neurotrauma, 2007, 24(6): 960 - 978.
  • 5Okonkwo DO, Povlishock JT. An intrathecal bolus of cyclosporin A before injury preserves miiochondrial integrity and attenuates axonal disruption in traumatic brain injury [J]. J Cereb Blood Flow Metab, 1999, 19(4): 443 - 451.
  • 6Reeves TM, Phillips LL, Lee NN, et al. Preferential neuroprotective effect of tacrolimus (FK506) on unmyelinated axons following traumatic brain injury [J].Brain Res, 2007, 1154:225 - 236.
  • 7Staal JA, Dickson TC, Chung RS, et al . Cyclosporin-A treatment attenuates delayed cytoskeletal alterations and secondary axotomy following mild axonal stretch injury [J]. Dev Neurobiol, 2007, 67(14): 1831 - 1842.
  • 8Okonkwo DO, Melon DE, Pellicane AJ, et al. Doseresponse of cyclosporin A in attenuating traumatic axonal injury in rat [J]. Neuroreport, 2003, 14(3): 463 - 466.
  • 9Goda M, Isono M, Fujiki M, et al. Both MK801 and NBQX reduce the neuronal damage after impact-acceleratation brain injury [J]. J Neurotrauma, 2002, 19(11): 1445 - 1456.
  • 10Royo NC, Shimizu S, Schouten JW, et al Pharmacology of traumatic brain injury [J]. Curr Opin Pharmacol, 2003, 3(1): 27 - 32.

共引文献25

同被引文献62

引证文献8

二级引证文献18

中华神经外科疾病研究杂志
2012年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部