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IgA1在过敏性紫癜性肾炎发病机制中的研究进展

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摘要 过敏性紫癜患者的长期预后与肾脏受累的严重程度有关,其肾损害的发生机制尚不明确,目前认为IgA1介导的免疫学异常在其中起重要作用。IgA1致过敏性紫癜患者发生肾损害的原因可能涉及IgA1分子发生异常糖基化,血清中IgA1水平升高,IgA1受体表达异常,补体参与,IgA特异性自身抗体异常等。
作者 孙玥 朱斌 朱彩凤
机构地区 浙江中医药大学 浙江中医药大学附属广兴医院
出处 《深圳中西医结合杂志》 2012年第2期114-116,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
基金 浙江省自然基金资助项目(Y207829 Y2101410) 杭州市科技局基金资助项目(20110733Q17)
关键词 紫癜性肾炎 异常糖基化 IGA1
分类号 R692.34 [医药卫生—泌尿科学]
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参考文献21

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深圳中西医结合杂志
2012年 第2期

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