摘要
目的 为探讨钚在国人体内的滞留与分布 ,对一例 2 0年前遭钚事故污染 (左手伤部可溶性钚摄入量约为 77～ 13 0Bq)者因肘部发生恶性纤维组织瘤而截下的右上臂进行了放化分析。方法 将手臂按解剖部位横向锯切成 8段 ,再将骨和软组织剥离 ,分别进行灰化、离子交换、电沉积制样并进行α能谱分析和活度测量。结果 在整个手臂中共测得2 39Pu含量为 68 5mBq ,α能谱分析证实手臂组织中钚的谱峰与2 39Pu标准源一致。这些2 39Pu 70 %滞留在骨组织中 ,其次是肌肉 ,皮肤约占 5 %。钚在骨中的分布是不均匀的 ,数据表明骨钚浓度C(mBq/g灰 )与灰 :湿重量比 (f)呈较好的负线性相关 ,C =0 72 - 1 2 6f ,r =- 0 78。结论 2 39Pu可在人的骨组织中长期滞留 ,主要沉积在骨骺端 ,骨干浓度较低 ,在骨内不同部位分布总趋势同国外报道一致。
Objective\ In order to study the retention and distribution of plutonium in human body.the activity in an amputated right arm from a patient with malignant fibrous histiocytoma developed at the elbow was analysed.The patient had been contaminated by plutonium intaken accidentally 20 years ago and the intake through a wound of his left hand was estimated to be 77～130 Bq. Methods The arm was dissected into 8 sections anatomically.Soft tissues were separated from bones.The samples were incinerated and the Pu was separated by ion exchange.Analysis of energy spectra and activity measurement were made after electrodeposition of the Pu on a stainless steel disc. Results The total content of 239 Pu in all of the samples was determined to be 68 5 mBq.The energy spectrum peak of Pu in arm tissues was the same with the standard source of 239 Pu.70% of the plutonium were retained in the bone.The content of 239 Pu in soft tissues was very low.About 5% of 239 Pu were detected in the skin.The distribution of Pu in bone was not uniform.The data show that the relationship between the concentration of plutonium in bone C(mBq/g ash) and the ratio of bone ash to its wet weight (f) was of a good negative correlation.It can be described by the linear equation,C=0.72-1.26f (correlation coefficient r =-0.78). Conclusion 239 Pu can deposit in the bone tissues of human body for a long time.The content of Pu in the epiphyseal ends is higher than in the diaphysis.The pattern of Pu distribution in bone noted in this paper is similar to that reported in the literature.\;
出处
《中华放射医学与防护杂志》
CAS
CSCD
北大核心
2000年第2期73-76,共4页
Chinese Journal of Radiological Medicine and Protection
