摘要
目的 :探讨参麦注射液合纳洛酮治疗重度急性酒精中毒的临床疗效。方法 :5 3例患者 ,随机分为两组 :治疗组 2 8例 ,参麦注射液静脉滴注 ,纳洛酮静脉注射 ;对照组 2 5例 ,仅用纳洛酮静脉注射。结果 :治疗组疗效良好 ,而且心电异常发生率为 42 .9% ;对照组为 6 0 .0 %。心电异常的持续时间 ,治疗组明显缩短 ,有显著差异 (P <0 .0 5 )。两组的催醒时间虽有差异 ,但无统计学意义。结论 :参麦注射液合纳洛酮治疗重度急性酒精中毒疗效显著 ,且能避免因纳洛酮剂量偏大所致的不良反应发生。
Objective: To observe the curative effects of Naloxone(NLX) combined with Shengmai Injection(SMI) on severe acute alcohol intoxication(SAAI). Methods: 53 cases with SAAI were randomly divided into the treatment group(n=28) and the control group(n=25). The treatment group was handled with NLX combined with SMI, the control group with NLX alone. Results: There was significant difference between the two groups(P<0.05)in the duration of cardioelectric abnormality.In the treatment group the incidence of cardioelectric abnormality and the duration of unconsciousness were 42.9% and 45.7±6.9(min) respectively, but in thecontrol group they were 60.0% and 48.8±7.2(min); there were no significant differences in awakening time ( P>0.05). Conclusion: The curative effects of SMI combined with NLX on ASAI are obvious and the harmful reactions caused by larger dosage of NLX can be avoided.
出处
《泸州医学院学报》
2000年第1期41-42,共2页
Journal of Luzhou Medical College
关键词
重度
急性酒精中毒
中西医结合治疗
Shengmai Injection
Naloxone
Severe acute alcohol intorxication
