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肝纤维化形成中血管紧张素(1—7)及其转换酶与胰岛素样生长因子结合蛋白2的动态变化 被引量:2

Dynamic alterations of angiotensin-converting enzyme, angiotensin-(1-7), and insulin-like growth factor binding protein-2 in fibrotic rat liver
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摘要 肝脏存在局部肾素一血管紧张素系统(RAS),血管紧张素1I(AngII)是其主要介质,AngⅡ在肝星状细胞活化与纤维增生中起重要作用。近年发现血管紧张素转换酶2(ACE2)及其代谢产物Ang-(1-7),Ang-(1-7)可通过Mas受体拮抗AngⅡ的作用,引起血管舒张、抑制细胞增殖。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2012年第5期392-394,共3页 Chinese Journal of Hepatology
关键词 肝硬化 肽基二肽酶A 血管紧张素类 胰岛素样生长因子结合蛋白2 Liver cirrhosis Peptidyl-dipeptidase A Angiotensins Insulin-like growth factor binding protein 2
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