摘要
目的通过对15例银杏达莫注射液致严重药品不良反应的文献进行分析,探讨其引起严重不良反应的规律和原因,为临床合理用药提供参考。方法对1995~2012年中国期刊全文数据库文献进行检索,对其中涉及银杏达莫注射液致严重药品不良反应的14篇文献中报道的15例病例报告进行统计与分析。结果与结论银杏达莫注射液致严重不良反应与剂量有关,多为速发型反应,过敏性休克患者的比例较高,严重程度高,临床应用应加强监测,密切防范不良反应的发生。
Objective Through analysing 15 Serious ADR cases of the Ginkgo Leaf Extract and Dipyridamole Injection to explore the rules and causes of adverse reactions, provide a reference for clinical rational use of drugs. Methods By searching literature from 1995-2012 Chinese journal full-text database, 14 Serious ADR literatures of Ginkgo Leaf Extract and Dipyridamole Injection involving 15 cases, were Statistically analyzed. Results and Conclusion Ginkgo leaf extract and dipyridamole injection induced serious ADR associated with dose. Ginkgo Leaf Extract and Dipyri- damole Injection-related adverse reaction, anaphylactic shock, a higher proportion of patients occurred a short time, serious high degree of clinical care should be strengthened and close to prevent the occurrence of adverse reactions.
出处
《中国药物警戒》
2012年第5期306-309,共4页
Chinese Journal of Pharmacovigilance
关键词
银杏达莫注射液
严重药品不良反应
文献分析
Ginkgo Leaf Extract and Dipyridamole injection
serious adverse drug reaction
literature analysis