摘要
目的:探讨肺栓塞(PE)的最佳治疗方案。方法:我院80例经CT检查确诊为肺栓塞的患者,采用溶栓、单纯抗凝法、手术/介入取栓法治疗,根据病情正确选择治疗方案,比较并分析不同治疗方案的临床疗效。结果:抗凝治疗26例,总有效率为92%,溶栓治疗39例,总有效率为87%,两组疗效比较差异有显著性(P<0.05),但病死率比较差异无显著性;手术/介入成功率为47%,病死率为14%,与溶栓组和抗凝组比较均有显著差异(P<0.05)。结论:早期诊断、早期治疗及根据病情采用不同的治疗措施对患者至关重要,加强抗凝治疗可明显降低肺栓塞患者的死亡率,改善预后。
Objective： To explore the best regimen of treatment of pulmonary embolism（PE） for early diagnosis and treatment to reduce patients＇ pain and mortality.Methods： Eighty patients with PE diagnosed by CT were treated with thrombolytic,anticoagulants,or embolectomy,and the outcomes were compared.Results： Of the 26 patients treated with anticoagulants alone,92% cases showed improvement in CT and clinical presentation,the percentage was significantly higher than that of the thrombolytic group whose rate of improvement was 87%（P0.05）.However,the rate of mortality were not significantly different between thrombolytic and anticoagulants alone.The success rate of embolectomy was 47%,but mortality rate was 14% which was significantly different from that of thrombolytic and anticoagulants alone respectively（both P0.05）.Conclusion： It is important of early diagnosis and treatment for PE patients to choose appropriate therapeutic regimen due to patients＇ condition.Mortality could be reduced and prognosis could be improved after anticoagulants treatment.
出处
《武汉大学学报（医学版）》
CAS
北大核心
2012年第3期430-433,共4页
Medical Journal of Wuhan University
关键词
肺栓塞
治疗选择
疗效评价
抗凝治疗
Pulmonary Embolism
Treatment Choice
Evaluation of Therapeutic Efficacy
Anticoagulants
