摘要
在失血性休克救治中,使用小容量的高渗盐（hypertonic saline,HS）溶液复苏能促进细胞内液、组织间液等转移入血管内,迅速扩充血容量,恢复有效循环血量,改善器官灌注.进一步研究发现,高渗盐主要具有以下三方面作用：①增强心肌收缩力,降低外周血管阻力,从而改善血流动力学;②抑制创伤后中性粒细胞和炎性细胞因子过度活化,调节免疫平衡;③减轻休克后肺损伤,降低颅内压,同时增加颅内灌注等,从而保护重要器官功能.
In the treatment of hemorrhagic shock, the use of small capacity of hypertonic saline solution can promote intracellular fluid and interstitial fluid to the transference to the blood vessels, the rapid expansion of blood volume, the recovery of effective circulating blood volume, the decrease of tissue edema. Hypertonic saline solution may increase myocardial contractility, reduce peripheral vascular resistance, regulate the immunity and protect vital organs function and so on.
出处
《中国急救医学》
CAS
CSCD
北大核心
2012年第5期458-461,共4页
Chinese Journal of Critical Care Medicine
