摘要
目的探讨重复使用戊巴比妥对比格犬麻醉剂量的影响。方法观察戊巴比妥反复多次对同一只比格犬使用后的剂量关系。结果戊巴比妥的使用剂量为:第1次(0.925 9±0.030 2)mL/kg、第2次(0.922 7±0.056 4)mL/kg、第3次(0.968 0±0.038 9)mL/kg),随着使用次数的增加,用药剂量逐渐增加(P<0.05),第4次[(1.306 3±0.185 5)mL/kg]用药剂量比前3次明显增加(P<0.05)。结论戊巴比妥重复使用后,随着使用次数增加,实际总用量将增加。
Objective To investigate the influence of repeatedly using pentobarbital on narcotic doses in Beagle dog.Methods To observe the dosage relation after repeatedly using pentobarbital at many times in the same Beagle dog.Results The dosage of pentobarbital was（0.925 9±0.030 2）mL/kg at the first time,（0.922 7±0.056 4）mL/kg at the second time and（0.968 0±0.038 9）mL/kg） at the third time.With the increase of use times,the dosage was gradually increased.The dosage of（1.306 3±0.185 5）mL/kg at the fourth time was significantly increased than the former three times（P〈0.05）.Conclusion After repeat use of pentobarbital,the practical total doses will be increased with the increase of use times.
出处
《重庆医学》
CAS
CSCD
北大核心
2012年第14期1400-1401,共2页
Chongqing medicine
基金
海南省重点科技计划基金资助项目(080217)
关键词
戊巴比妥
麻醉
影响
pentobarbital
anesthesia
effect
