期刊文献+

冬虫夏草固体发酵物水提液抗疲劳作用初步研究 被引量:4

Anti-fatigue Activity of Hot Aqueous Extracts of Ophiocordyceps sinensis Mycelium Evaluated Using a Mouse Model
下载PDF
导出
摘要 通过研究冬虫夏草(Ophiocordyceps sinensis)固体发酵物水提液对负重小鼠游泳时间的影响,初步探讨其抗疲劳作用。结果表明:与阴性对照组相比,灌胃喂养冬虫夏草固体发酵物水提液的小鼠负重游泳时间显著延长,证明在本试验条件下冬虫夏草固体发酵物具有显著的抗疲劳作用。 Ophiocordyceps sinensis mycelium was grown in 250 mL glass bottles on a solid medium consisting of 1% glucose,0.5% peptone,0.3% yeast extract and 0.3% malt extract in distilled water mixed with rice(1.5∶1).Hot(80-99 ℃) aqueous extracts of fungal mycelium grown for 25-30 d were administered to mice as part of their daily liquid intake(0.2 mL/10 g body weight) for 30 d and the anti-fatigue effects were evaluated using the weight-loaded swimming times of the mice as indicator.Extracts at a dose level of 1.27 g/kg·body weight had a significant(P0.05) anti-fatigue effect compared with untreated controls.
出处 《食用菌学报》 北大核心 2012年第1期61-64,共4页 Acta Edulis Fungi
基金 广东省基金项目(编号:10151007002000006) 广东省科技计划项目(编号:2009B080702029 2010A030100015) 广东省产学研项目(编号:2011B090400625)的部分研究内容
关键词 冬虫夏草 小鼠 抗疲劳 Ophiocordyceps sinensis hot aqueous extracts anti-fatigue effects in mice
  • 相关文献

参考文献14

  • 1KUO HC, SU YL, YANG HL, et al. Differentiation of Cordyceps sinensis by a PCR-single-stranded conformation polymorphism-based method and characterization of the fermented products in Taiwan[J]. Food Biotechnol, 2006, 20(2): 161-170.
  • 2CHEN JP, ZHANG WY, LU TT, et al. Morphological and genetic characterization of a cultivated Cordyceps sinensis fungus and its polysaccharide component possessing antioxidant property in H22 tumor-bearing mice[J]. Life Sci, 2006, 78(23) :2742-2748.
  • 3WANG SY, SHIAO M. Pharmacological functions of Chinese medicinal fungus Cordyceps sinensis and related species [J]. Journal of Food and Drug Analysis, 2000, 8(4): 248-257.
  • 4PATERSON RRM. Cordyceps--a traditional Chinese medicine and another fungal therapeutic biofactory?[J] Phytochemistry, 2008, 69(7):1469- 1495.
  • 5ZHOU X, GONG Z, SU Y, et al. Cordyceps fungi: natural products, pharmacological functions and developmental products[J]. Journal of Pharmacy and Pharmacology. 2009, 61 ( 3 ): 279-291.
  • 6NAGATA A, TAJIMA T, MORIYASU S. Effectiveness on ingestion with Cordyceps sinensis drinking during running exercise of humans [J]. Journal of Exercise Sports Physiology, 2002, 9: 85-92.
  • 7NAGATA A, TAJIMA T, UCHIDA M. Supplemental anti-fatigue effects of Cordyceps sinensis (Tochu-Kaso) extract powder during three step wise exercise in human [J]. Japanese Journal of Physiology Fitness Sports Medicine, 2006, 55: S145-S152.
  • 8HIYOSHI T, AKASU F, YOSHISUGU M, et al. Supplemental effects of Cordyceps sinensis extract on long distance runners [J]. Japanese Journal of Physical Fitness and Sports Medicine, 1996, 45(1): 205-210.
  • 9郑伟,王忠,谷顺才,郝爱功,韩艳丽,钟方虎,齐颖,肖爱珍,程杰,辛益妹,李广道.三种冬虫夏草制剂抗疲劳作用的比较[J].航空军医,2003,31(2):49-50. 被引量:4
  • 10陈新霞,吕中明,石根勇,徐德洲.冬虫夏草菌丝体的抗疲劳作用研究[J].中国生化药物杂志,2009,30(5):321-323. 被引量:13

二级参考文献25

  • 1翟鹏贵,赵珺彦,祝铃栋,朱耘.西洋参制剂抗疲劳作用的实验研究[J].浙江中医药大学学报,2007,31(6):761-762. 被引量:15
  • 2刘协,胡启之,李小宁,包六行.松花粉的抗疲劳作用研究[J].中国生化药物杂志,2004,25(3):169-170. 被引量:27
  • 3肖爱珍,王忠,谷顺才,郝爱功,韩艳丽,齐颖,辛益妹,李广道,郑伟,程杰.芦荟及其复方制剂的抗疲劳作用[J].航空军医,2003,31(6):249-250. 被引量:6
  • 4林萍,伍扬.藤茶抗炎作用的实验研究[J].四川中医,2006,24(9):12-14. 被引量:12
  • 5保健食品检验与评价技术规范[M].北京:人民卫生出版社,2003:97-104.
  • 6王裕生,邓文龙,薛春生,等.中药药理与应用[M].第2版,北京:人民卫生出版社,1998:646.
  • 7Booth F W, Thomason D B. Molecular and cellular adaptation of muscle in response to exercise : perspectives of various models [ J ]. Physiol Re'v, 1991,71 ( 2 ) :541.
  • 8[4]ww.fda.gov/cder/cancer/animalframe.htm
  • 9[5]FDA Guidance for industry and reviewers: Estimating the safe starting dose in clinical trials for therapeutics in adult healthy volunteers[ S]. 2002; 12
  • 10[6]FDA Guidance for Industry: food-effect bioavailability and fed bioequivalence studies[ S]. 2002; 12

共引文献1414

同被引文献56

引证文献4

二级引证文献32

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部