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不同剂量地佐辛用于剖宫产术后静脉镇痛效果比较 被引量:12

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摘要 目的:比较不同剂量地佐辛用于剖宫产术后静脉镇痛临床效果。方法:选择60例(ASAⅠ-Ⅱ级)剖宫产手术患者随机分为A、B、C 3组。A组:地佐辛0.3 mg.kg-1+托烷司琼5 mg,加生理盐水至150 ml;B组:地佐辛0.5 mg.kg-1+托烷司琼5 mg,加生理盐水至150 ml;C组:地佐辛0.7 mg.kg-1+托烷司琼5 mg,加生理盐水至150 ml。所有患者均采用持续静脉泵入给药模式,设定背景剂量3 ml.h-1,单次给药3 ml,锁定时间18 min,胎儿娩出后给予地佐辛负荷剂量5 mg、托烷司琼3 mg静脉滴注,术毕接静脉止痛泵。结果:B、C组VAS评分明显低于A组(P<0.05);C组Ramsay镇静评分明显高于A、B组(P<0.05);C组的不良反应(皮肤瘙痒,头晕,恶心)发生率明显高于A、B组(P<0.05)。结论:0.5 mg.kg-1地佐辛用于剖宫产术后静脉镇痛效果确切,不良反应发生率低,是适用于此手术的适宜剂量。
作者 秦忠芳
出处 《现代医学》 2012年第2期222-224,共3页 Modern Medical Journal
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