摘要
目的:研究泰山散瘀膏的抗炎镇痛作用。方法:取小鼠32只,随机分为致炎液实验组及致炎液对照组、冰醋酸实验组及冰醋酸对照组,每组8只,利用致炎液建小鼠耳廓肿胀模型,观察泰山散瘀膏的抗炎作用;采用小鼠醋酸扭体法研究泰山散瘀膏的镇痛作用。结果:泰山散瘀膏能显著降低小鼠耳廓肿胀程度,显著抑制冰醋酸所知疼痛后的扭体次数。结论:泰山散瘀膏具有明显的抗炎阵痛作用。
Objective :To study the anti-inflammatory arid analgesic effects of Taishan san yu ointment.Methods :32 mice were randomly divided into 4 groups. Empirical groups contained inflammation-inducing liquid group and glacial acetic acid group. In control groups, inflammation- inducing liquid group and glacial acetic acid group were also included. There were 8 mice in each group. The model of mouse auricle swelling was made up by inflammation-inducing liquid and used to observe the anti-inflammatory effect of Taishan san yu ointment. The method of acetic acid writhing used on the mice was adopted to research the analgesic effect of Taishan san yu ointment.Results :Taishan san yu ointment can markedly lower the degree of mouse auricle swelling and also can remarkably reduce writhing frequency which is induced by glacial acetic acid.Conclusion :Taishan san yu ointment has significant effect in anti-inflammation and analgesia.
出处
《中国医学创新》
CAS
2012年第13期22-23,共2页
Medical Innovation of China
关键词
泰山散瘀膏
抗炎
镇痛
实验研究
小鼠
Taishan san yu ointment
Anti-inflammation
Analgesia
Experimental study
Mouse