摘要
目的探讨大面积深度烧伤休克期切痂植皮的临床疗效。方法回顾性分析本院2009年3月～2011年12月收治入院的大面积深度烧伤休克期采用切削痂微粒皮移植术治疗的30例患者临床资料(休克期切痂组),另选择本院同期非休克期大面积深度烧伤患者采用切削痂微粒皮移植术治疗的30例患者(非休克期切痂组),对治疗结果进行回顾性分析。结果休克期切痂植皮组术后脓毒症、MODS等发生率、死亡率较非休克期切痂植皮组为低,P<0.05。休克期切痂组愈合时间也较非休克期切痂组快,且差异明显,P<0.05。休克期切痂植皮组患者3周内的IL-6、IL-8、TNF和LPS平均水平都明显低于非休克期切痂组(P<0.05或<0.01)。结论伤后及时清除创面坏死组织,并寻求积极有效地覆盖物封闭创面,对减少创面侵袭性感染、减少并发症,加快创面愈合,缩短病程,提高大面积深度烧伤治愈率至关重要。
Objective To study the large area deep burn shock stage for extensive clinical curative effect of skin grafts.Methods Retrospectively analyed in March 2009-December 2011 hospital were large deep burn shock stage using cutting scab skin particles of patients treated with the transplantation of 30 cases of clinical data （shock stage for extensive group）,another choose our hospital were not in the shock stage large area deep burn were treated by cutting the scab skin transplantation of particles treatment 30 patients （not shock stage for extensive group）,the treatment results were retrospectively analyzed.Results The shock stage for extensive skin grafts group began sepsis,MODS incidence,mortality was the shock stage for extensive skin grafts for the low group,P 0.05.Shock stage for extensive group was also the healing time shock stage for extensive group quickly,and the differences were significant,P 0.05.Shock stage cut scab skin grafts groups of patients within 3 weeks of IL-6,IL-8,TNF and LPS averages were significantly lower than the shock stage for extensive group （P 0.05 or 0.01）.Conclusion After injury cleared wound necrotic tissue and seek to effectively close wounds covering,to reduce the wound infection,and reduce the complications of invasive,accelerate wound healing,shorten the duration of symptoms,and improve the large area deep burn cure rate is very important.
出处
《中国当代医药》
2012年第13期36-37,39,共3页
China Modern Medicine
关键词
烧伤
保痂
混和移植法
微粒皮移植
Burned
The scab
Mixed tra lants
Particles skin grafting
