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重症急性胰腺炎合并甲状旁腺功能亢进高钙危象的临床分析 被引量:8

Clinical Study of Severe Acute Pancreatitis Complicated with Hypercalcemia Crisis in Hyperparathyroidism
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摘要 目的单纯重症急性胰腺炎及单纯甲状旁腺功能亢进症高钙危象在临床上均是危重疾病,本文探讨重症急性胰腺炎并发甲状旁腺功能亢进症高钙危象的临床表现、发病机制及诊治经验。方法回顾性分析重症急性胰腺炎合并甲状旁腺功能亢进症高钙危象患者的临床表现、实验室及影像学检查结果、治疗方法。结果本文4例患者在重症急性胰腺炎发病时血钙降低或正常,恢复期监测离子过程中发现血钙升高,考虑存在内分泌系统疾病,化验血清甲状旁腺激素并行超声定位,其中3例确诊为甲状旁腺瘤并均行手术切除,2例治疗痊愈,1例死亡,另1例未行手术治疗死亡。结论需注意胰腺炎并发甲状旁腺功能亢进症在临床表现、实验室检查及影像学特征方面的特异性,提高诊断,避免延误诊治。 Objective Either severe acute pancreatitis or hypercalcemia crisis in hyperparathyroidism is a severe disease.The diagnosis is difficult and mortality is high in the patients with both conditions.Our aim was to study the clinical manifestations,mechanism,diagnosis and treatment of such cases.Methods A retrospective study was made on the clinical manifestations,results of laboratory and diagnostic tests and treatment of serve acute pancreatitis patients complicated with hypercalcemia crisis in hyperparathyroidism.Results At the attack of severe acute pancreatitis,the level of blood calcium was lower or normal,while during the recovery,blood calcium increased,which indicated endocrine diseases.After being examined with PTH and ultrasound or CT location,three cases were diagnosed as parathyroid adenoma and undergone resection.Two recovered,one died and another without operation also died.Conclusion Special attention should be paid to the clinical manifestations,results of laboratory and diagnostic tests and diagnosis of the patients with serve acute pancreatitis patients complicated with hyperparathyroidism.
出处 《中国医科大学学报》 CAS CSCD 北大核心 2012年第5期446-449,共4页 Journal of China Medical University
关键词 急性重症胰腺炎 甲状旁腺功能亢进症 高钙危象 serve acute pancreatitis; hyperparathyroidism; hypercalcemia crisis
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  • 1Jeroen I Lenz,Jimmy M Jacobs,Bart Op de Beeck,Ivan A Huyghe,Paul A Pelckmans,Tom G Moreels.Acute necrotizing pancreatitis as fi rst manifestation of primary hyperparathyroidism[J].World Journal of Gastroenterology,2010,16(23):2959-2962. 被引量:10
  • 2彭圣威,姜亚平.原发性甲状旁腺功能亢进症误诊8例分析[J].中国误诊学杂志,2006,6(18):3570-3570. 被引量:6
  • 3Lee NC,Norton JA.Multiple-gland disease in primary hyperparathyroidism: a function of operative approach? Arch Surg,2002,137: 896-900.
  • 4Van Heerden JA,Grant CS.Surgical treatment of primary hyperparathyroidism: an institutional perspective.World J Surg,1991,15: 688-692.
  • 5Silverberg SJ,Shane E,Jacobs TP,et al.A 10-year prospective study of primary hyperparathyroidism with or without parathyroid surgery.N Engl J Med,1999,341: 1249-1255.
  • 6Chen H.Surgery for primary hyperparathyroidism: what is the best approach? Ann Surg,2002,236: 552-553.
  • 7Flint RS,Harman CK,Carter J,et al.Primary hyperparathyroidism:referral patterns and outcom of surgery.ANZ J Surg,2003,72 : 200-220 .
  • 8Wang CA.Surgical management of primary hyperparathyroidism.Curr Prob Surg,1985,22: 1-50.
  • 9Bergenfelz A,Lindblom P,Tibblin S,et al.Unilateral versus bilateral neck exploration for primary hyperparathyroidism: a prospective randomized controlled trial.Ann Surg,2003,236: 543-551.
  • 10Lumach F,Zucchetta P,Marzola MC,et al.Advantages of combined technetium-99m-sestamibi scintigraphy and high-resolution ultrasonography in parathyroid localization: comparative study in 91 patients with primary hyperparathyroidism.Eur J Endocrinol,2000,143

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  • 1郭鹏威,林栩,王洁,杨发奋,李仕良,黄鹏.用持续性与间歇性血液净化法治疗重症急性胰腺炎合并急性肾衰竭的疗效比较[J].当代医药论丛,2014,12(14):244-245. 被引量:4
  • 2朱海杭,徐永居,张利.以急性胰腺炎为首发表现的甲状旁腺功能亢进一例[J].中华消化杂志,2007,27(6):408-408. 被引量:5
  • 3孟迅吾,沙力进.协和内分泌代谢学[M].北京:北京科学出版社,2000:1464-1477.
  • 4Cusano NE, Silverberg SJ, Bilezikian JP. Normocalcemic primary hy- perparathyroidism[ J]. J Clin Densitom,2013,16(1) :33-39.
  • 5Rejnmark L, Amstrup AK, Mollerup CL,et al. Further insights into the pathogenesis of primary hyperparathyroidism: a nested case-control study[J]. J Clin Endocrinol Metab,20!3,98( 1 ) :87-96.
  • 6Lewiecki EM, Miller PD. Skeletal effects of primary hyperparathyroi dism: bone mineral density and fracture risk [ J ]. J Clin Densitom, 2013,16 ( 1 ) :28-32.
  • 7Cope 0, Culver PJ, Mixter CG Jr, et al. Pancreatitis, adiagnostic clue to hyperparathyroidism[J]. Ann Surg, 1957, 145(6): 857-863.
  • 8Jacob JJ, John M, Thomas N, et al. Does hyperparathy- roidism cause pancreatitis? A South Indian experience and a review of published work [J ]. ANZ J Surg, 2006, 76(8): 740-744.
  • 9Banks PA, Freeman ML. Practice guidelines in acute pancreatitis[J]. Am J Gastroenterol, 2006, 101(10): 2379- 2400.
  • 10Camaille B, Oudar C, Pattou F, et al. Pancreatitis and primary hyperparathyroidis forty cases[J]. Aust N Z J Surg, 1998, 68(2): 117-119.

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