摘要
目的比较丙泊酚和咪唑安定复合哌替啶在门诊无痛结肠镜检查中的临床效果和安全性。方法将80例拟行无痛结肠镜检查患者随机分为P组(丙泊酚1.5 mg/kg)和MM两组(咪唑安定0.05 mg/kg+哌替啶1.5 mg/kg),观察患者给药前、插镜时、睁眼时的血压、心率、血氧饱和度,记录麻醉期间的不良反应例数、肠镜检查时间、清醒时间以及VAS疼痛评分。结果两组患者麻醉过程中各时相点血压、心率、血氧饱和度差异均无统计学意义(P>0.05);P组肠镜检查时间和清醒时间均短于MM组,差异有统计学意义(P<0.05);P组VAS评分低于MM组,差异有统计学意义(P<0.05)。结论丙泊酚和咪唑安定复合哌替啶均可很好地完成门诊无痛结肠镜检查,而丙泊酚相对来说更具优点,值得推广。
Objective To compare the clinical efficacy and safety of Propofol and Midazolam combined with Meperidine application in outpatient colonoscopy.Methods 80 cases of outpatients who underwnent colonoscopy were randomly divided into group P who was given 1.5 mg/kg Propofol treatment and group MM who was given 0.05 mg/kg Midazolam combined with 1.5 mg/kg Meperidine treatment.The blood pressure（MAP）,heart rate（HR）,saturation of blood oxygen（SpO2） were observed before medication,during insert colonoscopy and opening eyes,and the adverse effect during anesthesia,colonoscopy detection time,recovery time,visual analog scale（VAS） scores were recorded.Results The blood pressure（MAP）,heart rate（HR）,saturation of blood oxygen（SpO2） were compared between the two groups,the differences were not significant（P 0.05）.The colonoscopy detection time and recovery time of group P were significantly shorter than those of the group MM（P 0.05）.The group P had lower VAS scores than the group MM（P 0.05）.Conclusion Propofol and Midazolam combined with Meperidine all can perform well in outpatient colonoscopy.However,Propofol has more advantages than Midazolam combined with Meperidine,which is worthy of being promoted.
出处
《中国医药导报》
CAS
2012年第14期103-104,111,共3页
China Medical Herald
关键词
丙泊酚
咪唑安定
哌替啶
结肠镜检查
门诊
Propofol
Midazolam
Meperidine
Colonoscopy
Outpatient clinic
