摘要
综述和分析了抗肿瘤药物近年来的新进展 ,包括细胞毒性抗肿瘤药物、以细胞信号转导分子为靶点的抗肿瘤药物、新生血管生成抑制剂、耐药逆转剂、反义药物。
Recent developments and approaches in anti tumor drug were reviewed and analysed in this manuscript, including new agents of traditional cytotoxity, protein tyrosine kinase inhibitors, farnesyltransferase inhibitors, tumor angiogenesis inhibitors, resistance reversal agents, antisense oligodeoxyribonucleotides, telomerase inhibitors and so forth.
出处
《中国新药杂志》
CAS
CSCD
2000年第3期149-154,共6页
Chinese Journal of New Drugs
关键词
抗肿瘤药物
细胞毒性
拓扑异构酶
酪氨酸激酶
Anti tumor drug
Cytotoxicity
Topoisomerase
Tyosine kinase
Farnesyltransferase
Angiogenesis
Telomerase