摘要
目的观察人免疫缺陷病毒（HIV）男性患者并发丙型肝炎病毒（HCV）感染后HCV抗体的表达情况，探讨影响HCV抗体表达的因素。方法选取经筛选检测最终确诊的HIV／HCV并发感染男性患者23例，每隔3个月随访一次共随访6个月。检测HIV及HCV病毒载量、CD4^＋T细胞计数及HCV抗体。结果首次HCVRNA拴测阳性时78．3％的患者HCV抗体阴性；3个月后，34．8％的患者为HCV抗体阴性；6个月后，17．4％的患者HCV抗体为阴性。结论HIV并发HCV的男性感染者，HCV抗体阳性率表达较低，应早期联合核酸检测。
Objective To estimated the positive rates of antibodies and the influencing factors of antibodies expansion in Hu- man immunoddficiency virus（HIV） men infected with hepatitis C virus（HCV）. Methods 23 HIV-positive patients with ear- ly HCV infection were identified. Plasma samples obtained at 3 monthly intervals（total 6 month） for routine monitoring of HIV and HCV viral load,CD4 cell counts, HCV antibodies. Results On first amplification of HCV, 78. 3 % of patients were serologically negative. Antibody detection remain seronegative 34. 8% by 3 months to 17.40% at 6 months. Conclusion The lower of HCV antibodies positive rates in HIV men with HCV should early combination of nucleic acid testing.
出处
《现代检验医学杂志》
CAS
2012年第2期99-100,103,共3页
Journal of Modern Laboratory Medicine
关键词
艾滋病病毒
丙型肝炎病毒
抗体
chronic obstructive pulmonary disease polymorphonuclear neutrophils mitochondrion
