期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

缺血性卒中的抗氧化治疗 被引量：4

Antioxidant therapy in ischemic stroke
原文传递
导出
摘要 氧化应激是缺血性卒中神经元损害的重要病理学机制之一，抗氧化治疗已成为缺血性脑损伤治疗的重要措施之一。文章就缺血性卒中的抗氧化治疗进展进行了综述。 Oxidative stress is one of the important pathological mechanisms of neuron damage in ischemic stroke.Antioxidant therapy has become one of the important measures for ischemic brain injury.This article reviews the advances in research on the antioxidant therapy of ischemic stroke.
作者 朱震寒 沙杜鹃 张均
机构地区 南京医科大学鼓楼临床医学院急诊科 南京大学附属南京市鼓楼医院急诊科
出处 《国际脑血管病杂志》 北大核心 2012年第4期289-294,共6页 International Journal of Cerebrovascular Diseases
关键词 卒中 脑缺血 抗氧化药 氧化性应激 Stroke Brain Ischemia Antioxidants Oxidative Stress
分类号 R743.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献81

  • 1Marsh JD,Keyrouz SG. Stroke prevention and treatment[J].Journal of the American College of Cardiology,2010.683-691.doi:10.1016/j.jacc.2009.12.072.
  • 2Bolai(n)os JP,Moro MA,Lizasoain I. Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke:Therapeuticimplications[J].Adv Drug Deliiv Rev,2009.1299-1315.
  • 3Brouns R,De Deyn PP. The complexity of neurobiological processes in acute ischemic stroke[J].Clin Neurol Neurosung,2009.483-495.
  • 4Crack PJ,Taylor JM. Reactive oxygen species and the modulation of stroke[J].Free Radical Biology and Medicine,2005,(11):1433-1444.doi:10.1016/j.freeradbiomed.2005.01.019.
  • 5Loh KP,Huang SH,De Silva R. Oxidative stress:apoptosis in netronal injury[J].Current Alzheimer Research,2006.327-337.
  • 6Allen CL,Bayraktuan U. Oxidative stress and its role in the pathogenesisof ischaemic stroke[J].International Journal of Stroke,2009.461-470.doi:10.1111/j.1747-4949.2009.00387.x.
  • 7Turrens JF. Mitochondrial formation of reactive oxygen species[J].The Journal of Physiology,2003.335-344.doi:10.1113/jphysiol.2003.049478.
  • 8Moro MA,Almeida A,Bola(n)os JP. Mitochondrial respiratory chain and free radical generation in stroke[J].Free Radical Biology and Medicine,2005,(10):1291-1304.doi:10.1016/j.freeradbiomed.2005.07.010.
  • 9Andreyev AY,Kushnareva YE,Starkov AA. Mitodhondrial metabolism of reactive oxygen species[J].Biochemistry(Moscow),2005.200-214.
  • 10Bedard K,Krause KH. The NOX family of ROS-generating NADPH oxidases:physiology and pathophysiology[J].Physiological Reviews,2007,(1):245-313.doi:10.1152/physrev.00044.2005.

二级参考文献78

共引文献24

同被引文献76

  • 1吴彬,胡胜娣,潘慧,祝世功.可卡因-苯丙胺调节转录肽激活ERK促进海马神经元合成BDNF[J].中国病理生理杂志,2007,23(7):1289-1292. 被引量：10
  • 2Spiess J, Villarreal J, Vale W. Isolation and sequence analysis of asomatostatin-like polypeptide fix>m ovine hypothalarms. Biodianistry,1981,20: 1982-1988.
  • 3Douass J,McKinzie AA, Couceyro P. PCR differential displayidentifies a rat brain mRNA that is transcriptionally regulated bycocaine and anphetamine. J Neurosci, 1995,15: 2471-2481.
  • 4Zhang M, Han L, Xu Y. Roles of cocaine- and amphetarnine-regilatedtranscript in the central nervous system Clin Exp Pharmacol Physiol,2012, 39:586-592.
  • 5Domingiez G. The CART gpne: structure and regilation. Peptides,2006,27: 1913-1918.
  • 6Douass J, Daoud S. Characterization of the human cDNA and興omic DNA encoding CART: a cocaine-and anphetamine-regulated transcript. Gene, 1996, 169: 241-245.
  • 7Dey A,Xhu X,Carroll R, et al. Biological processing of the cocaineand arrphetamine-reilated transcript precursors by prohormoneconvertases, PC2 and PCI/3. J Biol Chem, 2003,278:15007-15014.
  • 8Kristensen P, Jud ME, Thim L, et al. Hypothalamic CART is anew anorectic peptide regulated by leptin. Nature, 1998,393: 72-76.
  • 9de Lartigue G, Dimaline R, Varro A, et al. Cocaine- and amphetamine-regalated transcript: stimulation of egression in rat v%il afferentneurons by cholecystokinin and suppression by irelin. J Neurosci,2007,27:2876-2882.
  • 10Xu Y, Zhang W, Klaus J, et al. Role of cocaine- and anphetamine-regulated transcript in estradiol-mediated neuroprotection. Proc NatlAcad Sci USA, 2006, 103: 14489-14494.

引证文献4

二级引证文献9

国际脑血管病杂志
2012年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部