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谷胱甘肽硫转移酶的研究进展 被引量：11

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摘要 谷胱甘肽硫转硫酶（Glutathione S-transferases,GSTs）是广泛分布于各种生物体内的一组多功能同工酶,其主要功能是催化某些内源性或外来有害物质的亲电子基团与还原型谷胱甘肽的巯基偶联,增加其疏水性使其易于穿越细胞膜,并在被分解后排出体外,从而达到解毒的目的。本文对谷胱甘肽硫转移酶的分类、结构、功能进行阐述。
作者 冯雪 王彬 孙艳香
机构地区 河北省廊坊师范学院生命科学学院
出处 《生物学教学》 2012年第6期5-6,共2页 Biology Teaching
基金 廊坊市科技局科技支撑计划基金项目(2009012008) 廊坊师范学院教学改革课题基金(K2010-13)
关键词 谷胱甘肽硫转硫酶 结构 功能
分类号 Q55 [生物学—生物化学]
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参考文献13

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  • 2雷安平,陈欢,黎双飞,胡章立.谷胱甘肽S-转移酶的功能、应用及克隆表达[J].环境科学与技术,2009,32(12):85-91. 被引量：26
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二级参考文献92

  • 1郭桂芳,谢汝华.谷胱甘肽S-转移酶-π在头颈肿瘤中的研究进展[J].国外医学（耳鼻咽喉科学分册）,2005,29(1):15-18. 被引量：5
  • 2廖婉琴,梁旭方,王琳,方玲,雷腊梅,韩博平.淡水鱼类微囊藻毒素去毒酶基因的克隆[J].生态科学,2005,24(1):6-8. 被引量：10
  • 3段沁江.谷胱甘肽S－转移酶与肝脏病变研究的新进展[J].国外医学（卫生学分册）,1995,22(1):8-11. 被引量：10
  • 4张飚,李永清,高轩.谷胱甘肽S-转移酶综述[J].吉林畜牧兽医,2006,27(6):11-13. 被引量：11
  • 5丁橘.南极硅藻GJ01和南极衣藻ICE-L谷胱甘肽及其相关酶的研究[D].青岛:中国海洋大学,2005.
  • 6Rhee J S, Lee Y M, Hwang D S, et al. Molecular cloning and characterization of omega class glutathione S-transferase (GST-O) from the polychaete Neanthes succinea: Biochemical comparison with theta class glutathione Stransferase(GST-T) [J]. Comparative Biochemistry and Physiology, Part C,2007,146:471-477.
  • 7Lee Y M, Seo J S, Jung S O, et al. Molecular cloning and characterization of θ-class glutathione S-transferase (GSTT) from the hermaphroditic fish Rivulus marmoratus and biochemical comparisons with (x-class glutathione S-transferase (GST-A)[J]. Biochemical and Biophysical Research Communications, 2006,346:1053-1061.
  • 8Fan Chun-xin, Zhang Shi-cui, Liu Zhen-hui, et al. Identification and expression of a novel class of glutathione Stransferase from amphioxus Branchiostoma belcheri with implications to the origin of vertebrate liver[J]. The International Journal of Biochemistry & Cell Biology,2007,39: 450-461.
  • 9Abdallah M A, Pollenz R S, Droog F N, et al. Isolation and characterization of a cDNA clone coding for a glutathione S-transferase class delta enzyme from the biting midge Culicoides variipennis sonorensis Wirth and Jones[J]. Biochemical Genetics, 2000,38:11-12.
  • 10Liebau E, Miiller V, Lucius R, et al. Molecular cloning, expression and characterization of a recombinant glutathione S-transferase from Echinococcus multilocularisl[J]. Molecular and Biochemical Parasitology, 1996,77: 49-56.

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二级引证文献24

生物学教学
2012年 第6期

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