摘要
本文的实验进一步证实国人肝肾功能异常的血清EDLS明显高于正常人,尤其是进行肾透析的肾衰患者EDLS值更高,作者认为这可能与肾功能损伤程度更为严重有关。上述发现对指导临床合理使用地高辛具有重要意义。
cantly higher than that in normal subjects, especiallyin those who were undergoing hemodialysis. EDLSappears to has a direct relationship with the sever-eness of renal impairment. It was reported that endogenous degoxin-likesubstances (EDLS) exist in human bodies, especiallyin patients with liver diseases or renal impairmentand in premature infants. Since EDLS has a highaffinity to digoxin antibody, it often disturbs theresults of serum digoxin monitoring in immunoassaymethod. Our results showed that serum EDLS inpatients with liver or renal diseases was signifi-
出处
《中国药学杂志》
CAS
CSCD
北大核心
1990年第11期676-677,共2页
Chinese Pharmaceutical Journal
关键词
洋地黄样物质
EDLS
地高辛
EDLS
TD_x
digoxin
liver disease
renal impairment
