摘要
目的:探讨柴胡加龙骨牡蛎汤治疗围绝经期失眠的临床疗效。方法:将73例围绝经期失眠患者,随机分为治疗组(n=35),对照组(n=38)。治疗组予以柴胡加龙骨牡蛎汤治疗;对照组予以口服地西泮片治疗,治疗4周。观察2组临床疗效及治疗前后患者睡眠障碍量表(SDRS)的评分变化。结果:治疗组和对照组治疗的总有效率分别为91.42%和68.42%,差异有统计学意义(P<0.05);2组治疗后SDRS评分均较治疗前显著降低(P<0.05),治疗后2组间比较,治疗组显著低于对照组(P<0.05)。治疗组不良反应的发生率也显著低于对照组。结论:柴胡加龙骨牡蛎汤治疗围绝经期失眠疗效确切,安全性高,值得推广应用。
Objective：To investigate the curative effects of Chaihujialonggumulitang decoction in women with perimenopausal insomnia.Methods：Seventy three cases of perimenopausal insomnia patients were randomly divided into treatment group（n=35） and control group（n=38）.Patients in the treatment group were treated with Chaihujialonggumulitang decoction and patients in the control group were treated with diazepam tablets for 4 weeks.The curative effects and the SDRS scores of both groups were observed before and after treatment.Results： The total effective rates of the treatment group and the control group were 91.42% and 68.42%,respectively（P〈0.05）.Compared with before treatment,the SDRS scores in both groups significantly decreased after treatment（P〈0.05）.the SDRS scores in the treatment group were significantly lower than those in the control group after treatment（P〈0.05）.The treatment group also had less adverse effects than the control group.Conclusions： Chaihujialonggumulitang decoction has positive curative effects and high safety in treating perimenopausal insomnia.
出处
《中国临床医学》
2012年第2期175-176,共2页
Chinese Journal of Clinical Medicine
基金
上海市浦东新区卫生局基金项目(编号:PWZj2008-20-j13)
关键词
围绝经期
失眠
柴胡加龙骨牡蛎汤
疗效
Perimenopausal
Insomnia
Chaihujialonggumulitang decoction
Curative effect
