摘要
探讨不同血糖水平与高血压病发病共同危险因子。对１４９９人做了葡萄糖耐量试验（ＯＧＴＴ）及血浆胰岛素、血脂、尿微量白蛋白排泄率（ＵＡＥＲ）和体重、腰臀围比、血压等检测并进行了吸烟史、、每日吸烟量的调查。（１）在糖耐量低减（ＩＧＴ）和糖尿病（ＤＭ）组中，血压≥１８．７／１２．０ｋＰａ者的比例分别为４８．７％、５５．９％明显高于正常精耐量（ＮＧＴ）组的３２．２％，Ｐ＜０．０１；（２）ＩＧＴ和ＤＭ组的血糖、胰岛素、血脂水平、尿微量白蛋白排泄率、体重指数、年龄与ＮＧＴ组比较明显增高，Ｐ＜０．０５～Ｐ＜０．０１；（３）高血压组上述临床和生化指标与非高血压组比较也明显增设，均Ｐ＜０刀１；（４）多元逐步回归分析：血糖与胰岛素、血脂水平、ＵＡＥＲ、体重指数、血压、年龄、吸烟量呈显著正相关；血压也与上述项目及血糖呈显著正相关，Ｐ＜０．０５～Ｐ＜０．０１。糖尿病与高血压病存在共同危险因子，是相关性疾病，而且在糖耐量低减患者，这些危险因子已经存在，应早期进行综合干预。
The oral glucose tolerance test(OGTT )was performed on a crow of 1499 people. Additional investigations on hypertension and smoking as well as body mass index (BMI), waist to hip ratio (WHR), plasma insulin, lipids and urinary albumin excretion (UAER) were also performed. The following results were founds(l ) the proportion of hypertensive patients in DM and IGT group was higher than that of NGT group (p<0.ol ). (2 ) The comparison ofclinical characteristics Fasting and OGTTZ-h blood glucose and plasma insulin, blood lipid, UAER, BMI, Age between NGT and DM, IGT, P<0.01 or P<0.05. (3) The comparison of clinical characteristics between normal control and hypertension group, all p<0.ol. (4) The analyses of multiple setpwise regression indicated that blood pressure positively correlated to BMI, UAER, plasma insulin, lipids and number of cigarette smoking. Conclusions:Hyperglycemic state is a relevant disease to Hypertension and possess common risk factor, similar risk factor was also existed in IGT group, so that implied early intervention is necessary.
出处
《基础医学与临床》
CSCD
2000年第1期56-59,共4页
Basic and Clinical Medicine
关键词
高血压
高血糖
糖耐量试验
危险因子
hypeFtensiom
impaired glucose tolerance
normal glucose tolerance
