摘要锌指蛋白A20(zinc finger protein A20,A20)是近年来研究发现的一种抑制NF-κB(Nuclear factorκ-B)活性的负反馈调节蛋白,该蛋白通过这种负反馈调节可影响树突状细胞(DC)成熟和凋亡。本文就锌指蛋白A20的结构特点及其调控DC成熟和凋亡的作用机制作如下综述。
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