摘要
目的观察地诺前列酮栓与催产素在晚期妊娠引产中的有效性和安全性。方法:随机抽取于我院分娩的产妇300例,分为应用地诺前列酮栓引产的观察组和应用催产素引产的对照组,每组各150例,观察两组产妇宫颈Bishop评分、产程进展、顺产率,新生儿评分、产后出血情况。结果:观察组应用地诺前列酮栓12h后宫颈Bishop评分增加≥3分者105例(70%),对照组21例(14%);评分增加≥2分观察组42例(28%),对照组33例(22%);评分增加<2分者观察组3例(2%),对照组96例(64%),观察组宫颈Bishop评分明显高于对照组(P<0.05);观察组总产程7.12±1.25(h),对照组14.1±3.08(h),观察组总产程明显短于对照组;观察组顺产138例(92%),对照组96例(64%),观察组顺产率明显高于对照组(P<0.05)。结论:地诺前列酮栓用于妊娠晚期引产,能提高宫颈评分、加快产程进展、提高顺产率,效果优于催产素静脉点滴,可安全有效的应用于临床工作中。
Objective： To observe the efficacy and the safety of Dinoprostone suppositories and oxytocin used for induction of term pregnancy. Methods ： 300 pregnant women who had prenatal examined and delivered in our hospital were ran- domly divided into two groups： 150 cases as the observation group using dinoprostone and the other cases as the control group with oxytocin, and they were compared in cervical Bishop score, labor progress, newborn Apgar mark and postpartum bleeding. Results： The women who had dinoprostone after 12 houes whose cervical Bishop score increased by 〉 3 points accounted for 70% （105 cases） in the the observation group, and 14% （21cases） in the control group; those increased by /〉 2 points and by 〈2 points accounted for 28% （42 cases） and 2% （3 cases） in the the observation group, and22% （33cases） and 64% （96 cases） in the control group. The Bishop scores in the observation group were significantly higher than those in the control group （P 〈 0. 05 ）. The total stage of labor in the observation group was 7.12 ＋1.25 h, which was significantly shorter than that of controlsl4.1 ＋ 3.08h （P 〈 0.01 ）. The rate of normal labor through vagina in the ob- servation group was 92.0% （138 cases）, which was higher than that of 64.0% （96cases） in the control group （P 〈 0.01 ）. Conclusion： Dinoprostone for induction of labor in late pregnancy can improve the progress of labor, increase the cervical scores and the rate of normal labor, and has better results than oxytocin,which can be used safely and effectively in clinic. Key words： dinoprostone suppositories ; oxytocin; cervical score; induction of labor; labor
出处
《泰山医学院学报》
CAS
2012年第2期133-135,共3页
Journal of Taishan Medical College
关键词
诺前列酮栓
催产素
宫颈评分
引产
产程
dinoprostone suppositories
oxytocin
cervical score
induction of labor
labor
