摘要
目的探讨亚临床甲状腺功能减退(亚甲减)与老年高血压患者动态血压的关系。方法 233例老年高血压患者分为高血压合并亚甲减组35例(A组)及单纯高血压组198例(B组)。计算体质量指数,常规测定2组患者收缩期及舒张期血压、身高、体质量、空腹血糖、血肌酐、血尿酸、血脂水平、甲状腺功能及24h动态血压并分析相关指标。结果 A组舒张压、24h平均舒张压均高于B组(P<0.01,P<0.05);Logistic多元回归分析结果显示,随年龄增加舒张压水平呈下降趋势,随血清促甲状腺激素水平增高、吸烟史延长,舒张压水平呈上升趋势。结论舒张压控制不良的老年高血压患者应行甲状腺功能检查,有助于高血压病因的诊断。
Objective To investigate the relationship between subclinical hypothyroidism and ambulatory blood pressure in elderly hypertensive patients.Methods A total of 233 elderly hypertensive patients were divided into group of hypertension complicated with subclinical hypothyroidism（group A,n=35） and hypertension group（group B,n=198）.Systolic blood pressure,diastolic blood pressure,height,body mass,fasting plasma glucose,serum creatinine,uric acid,blood lipid level,thyroid function and 24-hour ambulatory blood pressure were measured.Results The levels of diastolic blood pressure and 24-hour diastolic blood pressure were higher in group A than those in group B（P〈0.01,P〈0.05）.Logistic multiple regression analysis showed that diastolic blood pressure decreased with the increasing of age,and increased with the increasing of serum thyroid hormone level and the prolong of smoking history.Conclusion Thyroid function tests should be performed in elderly hypertensive patients with poorly controlled diastolic blood pressure,which contributes to the diagnosis of hypertension etiology.
出处
《中华实用诊断与治疗杂志》
2012年第6期534-536,共3页
Journal of Chinese Practical Diagnosis and Therapy
基金
国家自然科学基金面上项目(81170120)
