摘要
目的评价美索巴莫在单纯肩关节脱位手法整复辅助治疗中的临床疗效和安全性。方法采用随机、平行对照的研究方法,将2009年4月至2010年10月收治的急性肩关节脱位患者100例分为治疗组和对照组各50例。治疗组给予美索巴莫注射液;对照组给予盐酸盐酸哌替啶注射液。复位前行药物治疗,对两组患者用药后1 h、2 h、3 h、4 h的疼痛程度及舒适度、复位成功的牵引时间及不良反应进行评估。结果两组疼痛治疗的有效率及舒适度、复位成功的牵引时间及不良反应均有显著差异(P<0.05),治疗组明显优于对照组,不良反应发生率治疗组低于对照组。结论美索巴莫是单纯肩关节脱位手法复位有效、安全的辅助药物。
Objective To evaluate the efficacy and safety on analgesia of methocarbamol in manipulatory reduction of shoulder joint dislocation. Methods A total of 100 patients with acute shoulder joint dislocation in this department during April 2009 to October 2010 were randomly divided into two groups. Fifty patients in trial group were administrated with methocarbamol, and fifty patients in control group were given with injection of pethidine hydrochloride. The evaluation of their outcomes included time for traction and reduction, degree of pain and comfort, adveme reactions while the reduction was applied at 1 h, 2h, 3h and 4h after administration of drug. Results There was significant difference in total efficacy between trial group and control group （ P 〈 0. 05 ）, the former was superior to that of latter （ P 〈 0. 05 ）, and adverse reactions were significandy lower in trial group than those in control group （ P 〈 0. 05 ）. Conclusion Methocarbamol is safe and effective in analgesia during reduction of shoulder joint dislocaion.
出处
《临床和实验医学杂志》
2012年第11期854-855,共2页
Journal of Clinical and Experimental Medicine
