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机械通气联合亚低温治疗神经源性肺水肿

Mechanical Ventilation Combined with Mild Hypothermia for the Treatment of Neurogenic Pulmonary Edema
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摘要 [目的]探讨机械通气联合亚低温抢救治疗神经源性肺水肿(NPE)的临床效果.[方法]对23例因各种原因并发NPE而转入ICU的患者随机分为两组,分别给予呼吸机机械通气联合亚低温治疗(亚低温组)和呼吸机治疗(综合组),治疗后1 h,2 h观察患者肺部啰音及动脉血氧饱和度(SaO2),同时进行血气分析.[结果]两组治疗均取得较好的效果,但两组比较,治疗后2 h血气指标及临床症状改善,差异有显著性(P〈0.05),亚低温治疗组取得更好疗效,且总生存率上升[结论]机械通气联合亚低温治疗能在较短时间内使肺水肿得到缓解,改善病人预后. [Objective]To explore the clinical efficacy of mechanical ventilation combined with mild hypother-mia for the treatment of neurogenic pulmonary edema(NPE). [Methods] Twenty three NPE patients who were caused by various reasons and turned into ICU were randomly divided into two groups. Mild hypothermia group was given breathing machine mechanical ventilation combined with mild hypothermia therapy. The synthesis group was given breathing machine mechanical ventilation. At lh and 2h after treatment, lung tales and SaO2 of patients were observed and meanwhile blood gas was analyzed. [Results]The therapeutic efficacy of two groups was good. Blood gas indicators and clinical symptoms 2h after treatment were improved, and there was significant difference between two groups( P〈0.05). Mild hypothermia group got better curative effect, and the overall survival rate increased. [Conclusion] Mechanical ventilation combined with mild hypothermia can release pulmonary edema in short time and improve the patients' prognosis.
出处 《医学临床研究》 CAS 2012年第5期866-868,共3页 Journal of Clinical Research
关键词 肺水肿/病因学 肺水肿/治疗 呼吸 人工 低温 人工 Pulmonary edema/ET Pulmonary edema/TH respiration,artificial hypothemia,induced
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