摘要
腰椎间盘突出是导致下腰痛及坐骨神经痛的主要原因。目前我国仍有部分患者受到腰腿痛的困扰,然而对本病的发病机制还不完全清楚。相关腰椎间盘突出发病机制的研究认为,腰椎间盘突出受多因素、多环节的影响,其发病主要与腰椎间盘退变、机械损伤、免疫损伤、炎性刺激等几方面因素的作用有关。现就腰椎间盘突出发病机制的国内外研究进展予以综述。
The lumbar intervertebral disc protrusion is the main cause of low back pain and sciatica.At present most people are still troubled in the problem of lumbocrural pain in China,however,the pathogenesis of the disease is not entirely clear.Researches concerning the pathogenesis of lumbar intervertebral disc protrution indicate that complex factors are related to the disease,mainly due to the degeneration of lunbar intervertebral disc,mechanical injury,immune damage and inflammatory and so on.Here is to make a review on the research progress at home and abroad of the pathogenesis of the disease.
出处
《医学综述》
2012年第11期1723-1726,共4页
Medical Recapitulate
关键词
腰椎间盘
突出
免疫组化
发病机制
Lumbar intervertebral disc
Protrusion
Immunohistochemistry
Pathogenesis
