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单核细胞趋化蛋白-1的作用机制研究进展 被引量:17

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摘要 趋化因子(chemokines)是一类小分子分泌性蛋白质,具有募集、活化特定白细胞的功能,并且对炎症反应的启动以及维持有着重要作用。趋化因子根据其分子氨基端两个高度保守的半胱氨酸残基位置,分为4个家族:C-X-C,CC,C和CX3C。单核细胞趋化蛋白-1(MCP-1/CCL2)属于cC趋化因子家族.其分子结构包括23个氨基酸组成的信号肽和76个氨基酸组成的成熟肽.
出处 《中华临床医师杂志(电子版)》 CAS 2012年第10期I0033-I0035,共3页 Chinese Journal of Clinicians(Electronic Edition)
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