摘要
目的:观察米非司酮治疗更年期功能失调性子宫出血的临床疗效。方法:选取我院自2006年3月至2010年5月收治的105例更年期功能失调性子宫出血患者按照治疗方法不同分为观察组(米非司酮治疗组)52例和对照组(去氧孕烯雌醇片)53例,比较两组患者的临床疗效。结果:观察组显效32例,有效16例,总有效率为92.3%;对照组显效21例,有效22例,总有效率为81.1%。两组总有效率比较差异显著(P<0.01),具有统计学意义。观察组与对照组治疗后性激素FSH、LH、E2及P水平比较均有显著性差异(P<0.01),具有统计学意义。结论:应用米非司酮治疗更年期功能失调性子宫出血效果理想,值得推广应用。
Objective： To observe the clinical effect of the treatment of mifepristone on climacteric dysfunctional uterine bleeding.Method： 105 patients with climacteric dysfunctional uterine bleeding treated in our hospital from March 2006 to May 2010 were selected and divided into 2 groups,the observation group（mifepristone treatment group）for 52 cases and the control group（desogestrel estradiol tablets treatment group） for 53 cases,and compared the clinical effects of the patients in 2 groups.Result：（1） As for the observation group,32 cases were significantly effective,16 cases were effectual with a total cure rate as 92.3%.As for the control group,21 cases were significantly effective,22 cases were effectual with a total cure rate as 81.1%.There was significant difference in the total cure rate of the 2 groups（P0.01）,which has statistical difference.（2） There was significant difference in the levels of sex hormone FSH,LH,E2 and P after treatment of the 2 groups（P0.01）,which has statistical difference.Conclusion： The effects of applying mifepristone to treat climacteric dysfunctional uterine bleeding is perfect,which is worthy popularization and application.
出处
《河北医学》
CAS
2012年第7期906-908,共3页
Hebei Medicine
