期刊文献+

蟾酥抗肿瘤有效成分的作用研究 被引量:11

Progress of Research on the Chemical Components of Venenum Bufonis and its Antitumor Effects
原文传递
导出
摘要 蟾酥(Venenum Bufonis)一词源自《本草衍义》,为我国名贵的传统中药。其含有多种化学成分,具有镇痛、强心、升压、局麻、抗炎和抗肿瘤等药理活性,临床应用广泛。蟾酥中抗肿瘤的有效成分为蟾毒配基类化合物,包括脂蟾毒配基、华蟾毒配基和蟾毒灵等。抗肿瘤活性主要包括诱导肿瘤细胞凋亡、抑制肿瘤细胞增殖、诱导肿瘤细胞分化等。近年来,有关蟾酥中活性成分在抗肿瘤方面的作用越来越成为国内外学者研究的热点。 Venenum Bufonis,the name of which origin from the Canon of Chinese Materia Medica Ben Cao Yan Yi,is a rare and valuable traditional Chinese medicine.It is widely applied in clinic,for it contains many chemical components and has functions in analgesia,strong heart,boosting pressure,local anesthesia,anti-inflammatory and antitumor.The active antitumor component of venenum bufonis is bufogenin compound,including bufogenin,cinobufagin,bufalin and so on.The antitumor activity mainly includes inducing apoptosis of tumor cells,inhibiting the cell proliferation and inducing the cell differentiation.In recent years,the antitumor effects of venenum bufonis and its active components has become research focus at home and abroad.
出处 《现代生物医学进展》 CAS 2012年第16期3185-3187,共3页 Progress in Modern Biomedicine
基金 陕西省自然科学基金:脂蟾毒配基和人参皂苷Rg3联合抗肿瘤作用机制研究(2010JQ4019)
关键词 蟾酥 化学成分 诱导凋亡 抑制增殖 诱导分化 细胞周期阻滞 Venenum Bufonis Chemical component Induce apoptosis Inhibit proliferation Induce differentiation Cell cycle arrest
  • 相关文献

参考文献11

二级参考文献82

共引文献210

同被引文献179

引证文献11

二级引证文献82

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部