期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

GDF15在肿瘤中的功能与作用机制的研究进展 被引量：2

Molecular Function and Mechanism of Growth Differentiation Factor 15 in Tumors
下载PDF
导出
摘要 生长分化因子15（growth differentiation factor 15．GDF15）又称前列腺衍生因子（prostate-derived factor，PDF）、胎盘转化生长因子。
作者 杨丞喆 钟来平 张陈平
机构地区 上海交通大学医学院附属第九人民医院.口腔医学院口腔颌面外科上海市口腔医学重点实验室
出处 《口腔颌面外科杂志》 CAS 2012年第3期219-222,共4页 Journal of Oral and Maxillofacial Surgery
基金 国家自然科学基金资助项目(30973344) 上海市科学技术委员会基金资助项目(1052nm04700 10140902200 10dz1951300) 上海交通大学医学院博士创新基金资助项目(BXJ201031)
关键词 GDF15 肿瘤 分子功能 分子机制 growth differentiation factor 15 tumor molecular function molecular mechanism
分类号 R730.2 [医药卫生—肿瘤]
  • 相关文献

参考文献28

  • 1Bauskin AR,Brown DA,Junankar S. The propeptide mediates formation of stromal stores of PROMIC-1:role in determining prostate cancer outcome[J].Cancer Research,2005,(06):2330-2336.doi:10.1158/0008-5472.CAN-04-3827.
  • 2Koopmann J,Buckhaults P,Brown DA. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers[J].Clinical Cancer Research,2004,(07):2386-2392.
  • 3Shnaper S,Desbaillets I,Brown DA. Elevated levels of MIC-I/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome[J].International Journal of Cancer,2009,(11):2624-2630.
  • 4Zhao L,Lee BY,Brown DA. Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling[J].Cancer Research,2009,(19):7696-7703.doi:10.1158/0008-5472.CAN-08-4901.
  • 5Zhang L,Yang X,Pan HY. Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma[J].Oral Oncology,2009,(07):627-632.doi:10.1016/j.oraloncology.2008.07.017.
  • 6Xue H,Lü B,Zhang J. Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach[J].Journal of Proteome Research,2010,(01):545-555.
  • 7Wallin U,Glimelius B,Jirstr(o)m K. Growth differentiation factor 15:a prognostic marker for recurrence in colorectal cancer[J].British Journal of Cancer,2011,(10):1619-1627.
  • 8Staff AC,Trovik J,Eriksson AG. Elevated plasma growth differentiation factor-15 correlates with lymph node metastases and poor survival in endometrial cancer[J].Clinical Cancer Research,2011,(14):4825-4833.
  • 9Brown DA,Stephan C,Ward RL. Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis[J].Clinical Cancer Research,2006,(01):89-96.
  • 10Baek SJ,Kim KS,Nixon JB. Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities[J].Molecular Pharmacology,2001,(04):901-908.

同被引文献25

  • 1花苏榕,张抒扬.生长分化因子-15基因多态性的研究进展[J].中华临床医师杂志（电子版）,2011,5(22):6688-6690. 被引量：3
  • 2Ago T, Sadoshina J. GDF15, a cardioprotective TGF-beta superfamily protein. Circ Res, 2006, 98: 294-297.
  • 3TobinJF, Celeste AJ. Bonemorphogenetic proteins and growth differentiation factors as drug targets in cardiovascular and metabolic disease. Drug Discov Today, 2006, 11: 405-411.
  • 4Bauskin AR, Brown DA, Kuffner T, et al. Role of macrophage inhibitory cytokine-1 in tumo- rigenesis and diagnosis of cancer . Cancer Res, 2006, 66: 4983-4986.
  • 5Kempf T, Sinning JM, Quint A, et al. Growth- differentiation factor-15 for risk stratification in patients with stable and unstable coronary heart disease: results from the AtheroGene study. Circ Cardiovasc Genet,2009,2 :286-292.
  • 6Bottner M, Suter-Crazzolara C, Schober A, et al. Expression of a novel member of the TGF-beta superfamily, growth/differentiation factor-15/ macrophage- inhibiting eytokine-l(GDF-15/MIC-1) in adult rat tissues. Cell Tissue Res, 1999,297 : 103-110.
  • 7Wollert KC. Growth-differentiation factor-15 in cardiovascular disease: from bench to bedside, and back . Basic Res Cardiol, 2007, 102:412-415.
  • 8Kempf T, Horn-Wichmann R, Brabant G, et, al. Circulating concentrations of growthdifferentiation factor-15 in,apparently healthy elderly individuals and patients with chronic heart failure as assessed by a new immunoradiometric sandwich assay. Clin Chem, 2007,53 : 284-291.
  • 9Kempf T, Eden M, Strelau J, et al. The transforming growth factor-beta superfamily member growth differentiation factor-15 protects the heart from ischemia/ reperfusion injury. Circ Res, 2006, 98: 351-360.
  • 10Mercer J, Bennett M. The role of p53 in atherosclerosis. Cell Cycle, 2006,5 : 1907-1909.

引证文献2

二级引证文献5

口腔颌面外科杂志
2012年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部