摘要
目的研究六味降抗合剂的制备、质量控制及临床疗效。方法建立该制剂的制备工艺,采用薄层色谱法对茵陈、黄芩、大黄、益母草、白芍、木香进行定性鉴别,采用高效液相色谱法对黄芩苷进行含量测定,并进行临床疗效观察。结果该制剂的制备工艺可行,质量可控;服药后孕妇及新生儿发病率为56.6%,死亡率为0,与服药前的发病率(90.0%)及死亡率(89.1%)相比,P<0.01。结论该制剂处方合理,制备工艺简单、质量可控,疗效确切,值得临床推广应用。
Objective To study preparation, quality control and clinical efficacy of Liuwei Jiangkang mixture. Method To establish the preparation process TLC was adopted to qualitatively identify capillaris,scutellaria,rhubarb,motherwort,peony,woody,usiug high HPLC to determine the content of baicalin, and to observe clinical efficacy. Results Possible preparation process of the preparation, quality is controllable; neonatal morbidity of pregnant women was 56. 6%, mortality was 0, and 90. 0% before treatment and the incidence of mortality compared to 89.1%, P 〈 0. 01. Conclusion The prescription is rational,preparation is simple, quality is controllable, and is worthy of clinical application.
出处
《中国药业》
CAS
2012年第11期36-38,共3页
China Pharmaceuticals
关键词
六味降抗合剂
制备
质量标准
临床应用
Liuwei Jiangkang Mixture
preparation
quality standards
clinical application
