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TCT法筛查宫颈病变临床结果分析 被引量:3

The value of Cervical Lesions with Cervical TCT Screening
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摘要 目的探讨液基薄层细胞学检测(TCT)技术在妇科子宫颈病变细胞学筛查中的临床应用价值。方法选择2006—12—2010-12来包头医学院第一附属医院妇科就诊并接受宫颈病变筛查的患者8492例。采用TCT技术检测及TBS分类标准诊断,对细胞学检查阳性者行阴道镜指引下多点活检,将细胞学检查结果与组织活检结果作比对分析。结果8492例TCT细胞涂片中,8465例为满意标本,细胞学阳性结果为430例,阳性检出率5.1%,其中351例经活检组织病理诊断,CIN及以上病例共243例,TCT的敏感度为69.2%;90例LSIL、58例HSIL及21例宫颈癌的细胞学检查与组织病理活检符合率分别为72.2%(65/90)、96.5%(56/58)、85.7%(18/21)。结论TCT检查能较为准确的反映宫颈病变情况,在妇科宫颈病变筛查中具有一定的临床应用价值。可作为临床宫颈癌及宫颈癌前病变的普查方法。 Objective To explore the clinical application value in cervical lesions with gynecologic cytology screening, using thinprep cytology test. Methods Select 8492 patients who accept screening for cervical lesions in our hospital from December 2006 to December 2010, adopt TCT detection and TBS Detection of diagnostic classification criteria. The cytology-positive patients take colposcopy biopsy under the guidance of multi-point, and then doing comparative analysis with cytology results and biopsy results. Results The 8465 cases were satisfied in 8492 cases ,the positive detection rate was 5.1% in 430 cytology positive cases of 8 465, 243 cases were CIN of 351 cases with biopsy, final cineidence rate between cervix Of uterus cytology and histopathologic was 69.2%. The coincidence rates of TCT and pathologic histology were 72.2 % ( 65/90 ) in LSIL, 96.5 % ( 56/58 ) in HSIL and 85.7 %( 18/21 ) in cervical carcinoma respectively. Conclusions TCT checking can exactly reflect cervical lesions. It can be used to check Cervical cancer with its high clinical application value in screening gynecological cervical lesions.
出处 《中国误诊学杂志》 CAS 2012年第17期4495-4497,共3页 Chinese Journal of Misdiagnostics
关键词 细胞诊断学/方法 宫颈疾病/诊断 Cytodiagnosis/methods Uterine Cervical Diseases/diagnosis
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  • 1Wang SS, Sheman ME, Hiled SA, et al. Cervical adenocarcino- ma and squamous cell carcinoma incidence trends among white women and black women in United States for 1976- 2000 [J]. Cancer, 2004,100(5) :1035-1044.
  • 2Renshaw AA, Young NA, Birdsong GG,et al. Comparison of perform ance of conventional and Thin-Prep gynecologic prepara- tion in the college of Amerian Pathologists Gynecologic Cytology Program [J]. Arck Pathol Lab Med,2004,128(1):17-22.
  • 3Confortini M, Bulgaresi P, Cariaggi MP,et al. Conventional pap smear and liquid-based cervical cytology smear: comparison from the same patient[J]. Tumori,2002, 88(4) : 288-290.
  • 4岑坚敏,钱德英,黄志宏,曾仁海,洪淡华.阴道镜对宫颈上皮内瘤变的诊断价值[J].中国实用妇科与产科杂志,2003,19(4):215-218. 被引量:231
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