摘要
从石竹科植物瞿麦 Dianthus superbus L.中分得 6种成分 ,经波谱分析鉴定为 :大黄素甲醚 (physcion, )、大黄素 (emodin, )、3,4-二羟基苯甲酸甲酯 ( )、3- (3′,4′-二羟基苯基 )丙酸甲酯 ( )、β-谷甾醇苷 ( )和大黄素 - 8- O-葡萄糖苷 (emodin- 8- O- glucoside, )。其中化合物 (2 0 0μg/kg)
Six compounds were isolated from the aerial parts of Dianthus superbus L.. By combination of physical constants and spectral analysis, their structures were identified as phycion (Ⅰ), emodin (Ⅱ), methyl 3,4 dihydroxybenzoate (Ⅲ), methyl 3 (3,4 dihydroxyphenyl) propionate (Ⅳ), β sito sterol 3 O glucoside (Ⅴ) and emodin 8 O glucoside (Ⅵ). All of these constituents were isolated from the title plant for the first time. Among them, compound Ⅲ showed potent anti pregnancy activity, given 200 μg/kg to pregnant rat can terminate pregnancy at its early stage of pregnancy.
出处
《中草药》
CAS
CSCD
北大核心
2000年第4期248-249,共2页
Chinese Traditional and Herbal Drugs
关键词
瞿麦
3
4-二羟基苯甲酸甲酯
大黄素
Dianthus superbus L. anti early pregnancy methyl 3, 4 dihydroxybenzoate
