摘要
目的分析染色体多态性对生育功能的影响,探讨其与ART妊娠结局的关系。方法回顾性调查分析珠海市妇幼保健院2009年至2010年生殖中心行IVF-ET共1607例患者的染色体核型及其临床资料,研究其ART妊娠情况。结果 1607例生殖异常患者中,检出染色体正常核型1563例(97.3%),ART妊娠877例,妊娠率为56.1%,流产113例,流产率为12.9%;检出染色体多态性核型37例(2.3%),ART临床妊娠20例,妊娠率为54.1%,流产2例,流产率为10.0%。结论染色体正常组与染色体多态性组ART的妊娠率及流产率的差异无显著性统计学意义,染色体多态性患者不影响ART妊娠结局。
Objective：Analysis of chromosome polymorphism of reproductive function,and to explore its relationship with pregnancy outcome in ART.Methods： A retrospective survey in our hospital form 2009 to 2010 Center for Reproductive clinic patients were karyotype and clinical data,visit the ART pregnancy outcome.Results：In all cases of reproductive abnormalities,and 1563 cases of normal Chromosome Karyotype（97.3%）were detected,ART pregnancy cases 877,pregnancy rate is 56.1%,113 cases of abortion,abortion rate was 12.9%;37 cases of chromosome karyotype polymorphism（2.3%） were detected,ART 20 cases of pregnancy,pregnancy rate was 54.1 %,2 cases of abortion,abortion rate was 10.0%.Conclusions：There was no difference in ART pregnancy rate and abortion rate between the normal chromosomes group and chromosome polymorphism group,chromosome polymorphism does not affect the ART pregnancy outcome.
出处
《中国优生与遗传杂志》
2012年第6期33-34,32,共3页
Chinese Journal of Birth Health & Heredity
关键词
染色体多态性
ART
妊娠结局
Chromosome polymorphism
ART
Pregnancy outcome
