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布托啡诺联合吗啡用于肛瘘切除术后硬膜外镇痛效果观察

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摘要 目的评估布托啡诺联合吗啡对肛肠手术患者术后硬膜外镇痛的效果及副作用发生情况。方法选择56例ASAⅠ∽Ⅱ级在连续硬膜外麻醉下施行肛瘘切除术的病人,随机分2组,每组28例,Ⅰ组手术结束前采用布托啡诺1 mg作为负荷量经硬膜外腔注入,术后留置硬膜外导管接镇痛泵行PCEA,镇痛液为:0.002%布托啡诺+0.002%吗啡+0.15%盐酸罗哌卡因+0.9%生理盐水共计100 ml;Ⅱ组手术结束前采用吗啡1 mg作为负荷量经硬膜外腔注入,术后PECA镇痛液:0.004%吗啡+0.15%盐酸罗哌卡因+0.9%生理盐水共计100 ml。参数设定都是背景剂量2 ml/h,PCA剂量1 ml/次,锁定时间15 min。观察术后镇痛效果以及皮肤瘙痒,恶心,呕吐和呼吸抑制等副作用的发生情况。结果两组方法镇痛效果无明显差异,但Ⅰ组皮肤瘙痒,恶心,呕吐和呼吸抑制等副作用发生情况明显少于Ⅱ组,病人满意度高,值得推广。结论 PECA联合使用吗啡和布托啡诺值得临床推广。
出处 《河南职工医学院学报》 2012年第3期306-307,共2页 Journal of Henan Medical College For Staff and Workers
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参考文献8

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