摘要
目的:研究并分析拥有飞行时间(TOF)技术的PET/CT相关性能。方法:参照美国国家电气制造协会(NEMA)NU2-2007标准和厂家测试手册,对PET/CT的能量与时间分辨率、空间分辨率、灵敏度、散射分数、计数特性和图像质量进行性能测试和分析,并对不同型号仪器的性能进行比较,初步探讨飞行时间(TOF)技术对设备性能的影响。结果:系统的能量分辨率和时间分辨率分别为11.59%和499.3ps;空间分辨率在1cm处为4.54mm(横向)和4.85mm(轴向),10cm处为5.13mm(横向径向)、5.55mm(横向切线)和5.76mm(轴向);中心和偏离中心10cm处的灵敏度分别为6.4和6.8(cps/kBq);散射分数为32%;等效噪声计数率(NECR)在14.03kBq/ml时达到峰值为97.6kcps;模体图像中可以清楚分辨直径为10mm的最小热球。结论:拥有飞行时间技术的PET/CT各项性能指标都很优越,尤其在于图像质量的提高,可以缩短采集时间和减少注射药物剂量。
Objective： The performances of a PET/CT scanner with time-of-flight （TOF） capability were measured and studied. Methods： Performances measurements on the scanner were made using the National Electrical Manufactures Association （NEMA） NU2- 2007 procedures and Company＇s Performance Test Manual. The energy/timing resolution, spatial resolution, sensitivity, the scatter fraction, counts performance and imaging quality were measured and analyzed. Different types of PET/CT were compared and the imagingcapabilities of TOF were discussed. Results： The system and 499.3 ps. The transverse and axial resolutions near energy and timing resolution were measured to be 11.59% the center were 4.54mm and 4.85mm, whereas at 10 cm were 5.13 mm, 5.55 mm, 5.76 mm. The absolute sensitivity of this scanner was 6.4（center） and 6.8（10 cm） cps/ kBq, whereas scatter fraction was 32%. The peak NECR was 97.6kcps and occured at 14.03kBq/mL. Image quality measurements with phantom showed that the 10 mm diameter lesion could be clearly distinguished. Conclusion： The PET/CT which achieved TOF capability performed good characteristic, especially in the improvement of image quality. And shorter scan times and lower dose could be gained at the same image quality.
出处
《中国医学装备》
2012年第7期1-5,共5页
China Medical Equipment
基金
国家自然科学基金(81071198)"肿瘤靶向纳米探针NIRF-CCPM-RGD的多功能分子影像研究"
