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MicroRNA与乳腺癌侵袭转移的关系 被引量：5

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摘要 文献报道显示乳腺原位癌与侵袭癌相关microRNA种类既有相同者,也有相异者。乳腺癌相关microRNA对癌变和(或)转移的调控能力有的兼具二者,有的仅具其一。microRNA对乳腺癌侵袭、转移的作用包括调控癌细胞迁徙、侵袭与生存能力,改变微环境与促进血管生成及启动瘤细胞上皮——间质转变。乳腺癌干细胞在microRNA调控下不仅促进乳腺癌发生,也与癌侵袭转移的发生、发展密切相关。
作者 张众 李连宏 Xiao Gray Guishan 石宇 谢丰培
机构地区 大连医科大学病理学教研室 Creighton University Medical Center Thomas Jefferson University Hospital
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2012年第7期713-716,共4页 Chinese Journal of Clinical and Experimental Pathology
关键词 癌侵袭转移 乳腺原位癌 MICRORNA MICRORNA 乳腺癌干细胞 细胞迁徙 血管生成 调控
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献25

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共引文献15

同被引文献49

  • 1马涛,张君莹,吴建中,唐金海.miR-342-3p对三阴性乳腺癌化疗敏感性的影响[J].中南大学学报（医学版）,2014,39(5):488-495. 被引量：8
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引证文献5

二级引证文献23

临床与实验病理学杂志
2012年 第7期

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