摘要
冠状动脉临界病变(ICS)是冠状动脉粥样硬化进展过程中的一个特殊阶段,通常是指冠状动脉造影(CAG)直径法测定冠脉某一阶段狭窄20%-70%的病变,其病因、病理同冠心病(CHD)一致,也是急性冠脉综合征(ACS)发生的主要原因,68%-70%的急性心肌梗死(AMI)患者冠脉狭窄的程度系临界病变。病理研究表明ACS的主要病理机制为易损斑块破裂并诱发血栓形成致相关冠脉狭窄或闭塞而发病。本文系统梳理了近年来有关冠脉临界病变研究的文献,对其研究进展做一综述,为其诊疗提供一定线索。
Intermediate coronary stenosis（ICS） is a special stage of coronary atherosclerosis progress,it is at least one segment of coronary diameter stenos is 20%-70% and its etiology agents,pathologic process are the same with those of coronary heart disease（CHD）.In addition,ICS is the principal cause of acute coronary syndrome（ACS）.Such degree of stenosis is unlikely to reduce coronary flow sufficiently enough to cause symptoms.Histopathological studies have shown that the principal pathologic process underlying most AMI is the rupture of an atherosclerotic plaque and following thrombosis.In this article,the author generalized the research survey on ICS of western and traditional Chinese medicine and then discussed possible research method in ICS of traditional Chinese medicine.The purpose is to provide the clues to the diagnosis and treatment of ICS.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2012年第7期1875-1878,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
首都医学发展科研基金(No.SF-2009-Ⅱ-02)
中国博士后科学基金资助上项目(No.20110490549)~~
关键词
冠状动脉临界病变
中西医研究进展
问题与展望
Intermediate coronary stenosis
Research progress of traditional Chinese and western medicine
Problems and prospects
