摘要
目的:探讨中医辨证治疗高效抗反转录病毒疗法(HAART)后高脂血症的临床疗效。方法:采用实用性随机对照研究的试验方法,对50例HAART治疗后高脂血症的受试者分别给予中医辨证或对照治疗,同时测定血脂、肝肾功能等指标。结果:中医辨证治疗可以显著降低血清总胆固醇(TC)和低密度脂蛋白(LDL-C)水平,对于甘油三酯(TG)的治疗虽然无统计学意义,但是治疗后TG水平也有明显的下降。对照组治疗后TC和TG水平有明显下降,但是高密度脂蛋白(HDL-C)和LDL-C治疗后无变化。结论:中医辨证治疗HAART治疗后高脂血症,可以发挥中医药优势,改善脂代谢异常,减小HAART的毒副作用,继而提高HAART的依从性和临床疗效。
Objective: To evaluate the clinical curative effect of hyperlipidemia with the treatment based on syndrome differentiation of TCM in highly active antiretroviral therapy.Methods: With the practical randomized controlled trials test methods,50 cases of hyperlipidemia subjects were given the treatment based on syndrome differentiation of TCM or controlled,at the same time testing blood lipid,liver and kidney function indexes.Results: the treatment based on syndrome differentiation of TCM can significantly reduce the level of TC and LDL-C,for the decline of TG not statistically significant,but the level of TG also have obviously reduced,in the control group the level of TC and TG have notablely lessened after the treatment,but HDL-C and LDL-C have no change.Conclusion: The treatment based on syndrome differentiation of TCM of hyperlipidemia can play a stronger role in highly active antiretroviral therapy,regulate lipid metabolism disorder and reduce the side effects of HAART,then perfect HAART compliance and clinical curative effect.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2012年第7期1973-1975,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家科技重大专项(No.2009ZX10005-015
No.2008ZX10005-003H)~~
关键词
艾滋病
高效抗反转录病毒疗法
高脂血症
中医辨证
Acquired immune deficiency syndrome
Highly active antiretroviral therapy
Hyperlipidemia
The treatment based on syndrome differentiation