摘要
[目的]了解济南市人群甲型H1N1流感(以下简称甲流)病毒抗体水平及其影响因素,为制定进一步的甲流防控策略提供科学依据。[方法]2010年1、3和8月,对济南市辖区内抽取历城区、历下区、槐荫区的4 576名健康人群进行甲流血清抗体检测,并采用非条件Logistic回归分析对影响人群甲流抗体水平的因素进行分析。[结果]2010年1、3、8月合计检测4 576人血清,甲流病毒抗体阳性率为21.15%。甲流病毒抗体阳性率,男性为23.56%,女性为19.21%(P<0.01);0～5岁为24.11%,6～15岁为25.50%,16～24岁为31.82%,25～59岁为13.08%,≥60岁为10.77%(P<0.01);学生为30.26%,幼托儿童为23.95%,其他职业为14.08%(P<0.01);近2周内曾有流感样症状者为23.34%,无症状者为18.38%(P<0.01);近2周内曾有发热者为27.48%,未发热者为18.49%(P<0.01);近2周内有咳嗽者为23.88%,无咳嗽者为19.24%(P<0.01);近2周内有咽痛者为23.03%,无咽痛者为20.37%(P<0.05);接种过甲流疫苗者为32.89%,未接种过者为20.34%(P<0.01)。非条件Logistic回归分析结果,与60～岁比较,0～5岁、6～15岁、16～24岁的甲流抗体阳性率较高;调查前2周内有发热者抗体阳性率高于没有发热者,接种过甲流疫苗者抗体阳性率高于没有接种过者;与其他职业比较,学生的阳性率较高。[结论]济南市城区健康人群甲流病毒抗体水平较低,接种甲流疫苗可明显提高抗体阳性率者。
[Objective]To understand the antibody level of influenza A（H1N1） and influential factors, so as to provide basis for the prevention and control. [Methods]A total of 4 576 healthy people were sampled from Licheng, Lixia and Hua iyin districts in January, March and August, 2011 respectively to test the antibody level and analyze the related factor with the non-conditional logistic regression analysis. [Resuits]A total of 4 576 serum samples were tested in January, March and August. The total antibody positive rate was 21.15 %. The positive rate of male was 24.11 %, female 19.21 % （P〈 0.01 ）. The positive rate of 0-5 years old was 23.56% ,6-15 years old was 25.50%,16 24 years old was 31.82%,25-59 years old was 13.08% ,≥60 years old was 10.77% （ P 〈0.01） ; the positive rate of student was 30.26%, kindergarten children 23.95 %,other occupation 14.08%（ P 〈0.01） ;the positive rate of the people with influenza like symptom 2 weeks ago was 23.34%, without symptom was 18.38% （ P 〈0.01） ;the peoplewith fever was 27.48 % ,without fever was 18.49/00 （ P 〈0.01） ; with cough 23.88%, without cough 19.24% （P〈0.01） ; with pharyngalgia 23.03%, without pharyngalgia 20.37%（ P 〈0.05）;the people inoculated with H1N1 influenza vaccine was 32.89% ,unvaccinated was 20.34% （P 〈 0.01）. The un-conditional logistic regression analysis showed that the positive rate of 0 5 years old people,6-15 years, 16- 24 years was higher than 60-years old. The people who had fever 2 weeks ago had higher positive rate than those without fever. The people inoculated with HIN1 influenza vaccine had higher positive rate than those unvaccinated. The positive rate of student was higher than other occupation. [Conclusion]The immunity of influenza A（H1N1） in Jinan city is low, Inoculation with H1N1 influenza vaccine can increase the positive rate obviously.
出处
《预防医学论坛》
2012年第7期489-490,496,共3页
Preventive Medicine Tribune
