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肺癌术后并发急性肾损伤的影响因素分析 被引量：1

The risk factors of acute kidney injury after lung cancer surgery
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摘要 目的探讨肺癌术后急性肾损伤(AKI)的影响因素及临床意义。方法回顾性分析527例肺癌手术患者,将发生AKI患者与非AKI患者进行危险因素分析。结果 39例患者发生AKI,总患病率为7.4%。ASA分级、低FEV1、糖尿病、Hct和手术时间是肺癌术后并发AKI的相关危险因素。Logistic多因素回归分析结果显示,ASA分级、低FEV1和手术时间是肺癌术后并发AKI的独立危险因素。结论肺癌术后AKI的发生容易被忽视,谨慎选择手术患者,术中注意维持血流动力学稳定,是预防肺癌术后AKI发生的关键。 Objective To evaluate the incidence and determinants of acute kidney injury （AKI） using the AKIN criteria in patients after lung cancer surgery. Methods We retrospectively analyzed a cohort of patients undergoing lung cancer surgery from 2008 to 2011. The primary outcome was AKI within 3 days after surgery. A variety of patient comorbidities and operative characteristics were evaluated as potential predictors of AKI using a Logistic regression model. Results Complete data were obtained from 527 patients. AKI occurred in the 39 patients （7.4% incidence）. Univariate analysis revealed that American Society of Anesthesiologists （ASA） physical status, low FEV1, diabetic, Hct and surgi- cal time related to AKI following lung cancer surgery. Logistic multivariate regression analysis showed that ASA physical status, low FEV1 and surgical time were independent risk factors for AKI. Conclusion The incidence of AKI after lung cancer surgery is closely related with risk factors. Our data suggest that lung cancer patients planning to accept surgery should be more comprehensively assessed and monitored, thereby preventing the occurrence of AKI.
作者 李静 柳斌 马行一
机构地区 四川省肿瘤医院 四川大学华西医院
出处 《西部医学》 2012年第7期1340-1342,共3页 Medical Journal of West China
关键词 肺癌 手术 急性肾损伤 Lung cancer Surgery Acute kidney injury
分类号 R734.2 [医药卫生—肿瘤]
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参考文献11

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二级参考文献21

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西部医学
2012年 第7期

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