摘要
目的分析使用米非司酮与米索前列醇联合的不同剂量在药物流产中的应用价值,以供药物流产中借鉴参考。方法将我院2010年3月至2011年9月收治的179例进行药物流产的患者随机分为两组,对照组患者每日空腹服用米非司酮25mg,间隔12h再服用一次,连续服用3d,并在第4日清晨服用米索前列醇600μg;实验组患者米非司酮用药方式同对照组,于第4日清晨和中午分别服用米索前列醇600μg,比较两组患者药物流产情况。结果实验组患者的流产成功率明显高于对照组患者,P<0.05;实验组出血天数更少,其平均出血天数低于对照组患者,P<0.05,差异有统计学意义。结论在米非司酮与米索前列醇常规用药基础上再加用600μg米索前列醇能够提高流产效果,缩短患者的阴道流血事件,具有较好的临床应用价值。
Objective Analysis using mifepristone and misoprostol combined with different doses of the medication abortion in the application, for reference of drug abortion. Methods In our hospital from 2010 March to 2011September,179 cases of drug abortion patients were randomly divided into two groups, control group patients daily fasting taking mifepristone25mg,12h interval to take time, take 3 days continuously, and in fourth days of early morning taking misoprostol 600 pg; patients in the experimental group with mifepristone medication the control group, in fourth early in the morning and noon respectively taking misoprostol 600u g, compared two groups of patients with drug abortion. Results The experimental group patients abortion rate was significantly higher than the control group patients, P〈0.05; the experimental group days less bleeding, the bleeding days less than patients in the control group, P〈0.05, the difference was statistically significant. Conclusion The routine use of mifepristone and misoprostol plus600u g misoprostol can improve abortion patients, shorten the vaginal bleeding events, has good clinical application value.
出处
《中国医药指南》
2012年第18期404-405,共2页
Guide of China Medicine
