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320排容积CT全脑灌注成像在急性缺血性脑血管病中的应用 被引量:16

Application of whole-brain CT perfusion imaging with 320-detector row CT in acute ischemic cerebrovascular diseases
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摘要 目的探讨320排容积CT全脑灌注成像在急性缺血性脑血管病(AICVD)中的应用价值。方法对20例临床拟诊为AICVD患者,于发病24h内行头颅CT平扫和全脑CT灌注(CTP)成像检查,获得脑血流量(CBF)、脑血容量(CBV)、平均通过时间(MTT)、达峰时间(TTP)等参数,同时获得动态CT血管成像(4D-CTA)图;于CTP检查后24h内复查MR,分析其CTP、4D-CTA及MRI表现。结果常规CT平扫示8例有脑缺血病灶,12例未见明显异常。全脑CTP20例患者共发现与临床症状相对应的32个缺血灶,MRI发现26个病灶表现为梗死灶。4D-CTA显示责任血管不同程度狭窄或闭塞,20例患者中14例血管狭窄,2例闭塞,4例正常。结论 320排容积CT全脑灌注成像可同时获得CTP、4D-CTA图像,实现对AICVD的全面评价。 Objective To explore the application of whole-brain CT perfusion(CTP) imaging with 320-detector row CT in patients with acute ischemic cerebrovascular diseases(AICVD).MethodsTwenty patients diagnosed as AICVD underwent plain CT and CTP within 24 h after the onset of symptoms.The parameter maps of cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time(MTT)and time to peak(TTP) were analyzed.Meanwhile dynamic CT angiography(4D-CTA) images were obtained.MR was performed within 24 h after CTP.ResultsEarly infarctions were found in 8 patients,and 12 patients showed normal on conventional plain CT,while 32 ischemic lesions corresponding to clinical symptoms were found in whole-brain CTP.MRI confirmed that 26 lesions were infarct foci.And 4D-CTA showed vascular stenosis in 14 patients,occlusion in 2 patients,and normal in 4 patients.ConclusionFull evaluation of AICVD can be achieved using whole-brain CT perfusion imaging with 320-detector row CT.
出处 《中国医学影像技术》 CSCD 北大核心 2012年第7期1290-1294,共5页 Chinese Journal of Medical Imaging Technology
关键词 缺血性脑血管病 体层摄影术 X线计算机 灌注成像 血管造影术 Ischemic cerebrovaseular diseases Tomography, X-ray computed Perfusion imaging Angiography
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