摘要
目的评估眼动脉血管反应性在2型糖尿病脑血管病变中的临床诊断价值。方法运用经颅多普勒诊断仪,对27例2型糖尿病患者和23例健康体检者行TCD检查,对比分析两组人群大脑中动脉(MCA)及眼动脉(OA)的平均血流速度(Vm)、搏动指数(PI)、屏气指数(BHI)的差异程度。结果糖尿病组与对照组比较,OA的平均血流速度(Vm)、屏气后的平均血流速度(Vm’)、屏气指数(BHI)均降低,与对照组比较均有统计学意义;糖尿病组与对照组比较,MCA的搏动指数(PI)、屏气后的搏动指数(PI’)均增高,与对照组比较均有统计学意义。结论糖尿病患者MCA、OA的脑血管反应性检测,能早期识别2型糖尿病大血管和微血管病变,为2型糖尿病患者早期及时提供防治依据。
Objective Estimate the ophthalmic artery blood vessel reactivity in cerebrovascular pathological changes of 2 diabetes patients. Methods Consecutive patients with type 2 diabetes were compared with age-matched 23 controls. The velocities of MCA and ophthalmic artery （ OA）, the putsation index （PI） and the breath-holding index （BHI） were recorded. Results The velocities of OA and BHI in diabetes groups was significantly lower than that of the control groups（P 〈 0.05）. The putsation index （PI） of MCA was reduced in patients with type 2 diabetes as compared with controls （P 〈 0.05）. Conclusion TCD measurement of CVR may be useful for the diagnosis microvascular diseases including retinopathy and macrovascular complications in diabetes.
出处
《中华脑血管病杂志（电子版）》
2012年第3期12-15,共4页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
基金
国家自然科学基金资助项目(81070923
81100870)
南京军区南京总医院院管课题资助项目(2011045)
关键词
2型糖尿病
视网膜病变
脑血管反应性
大脑中动脉
眼动脉
2 diabetes
Retinopathy
Cerebrovascular reactivity
Middle cerebral artery
Ophthalmic artery
