阿司匹林联合氯吡格雷治疗不稳定型心绞痛疗效及安全性观察被引量：17

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摘要目的探讨阿司匹林与氯吡格雷联合治疗不稳定型心绞痛(UAP)的临床疗效及安全性。方法将82例UAP患者随机分成治疗(n=42)和对照(n=40)组,两组均应用常规控制心绞痛、调脂、抗凝及阿司匹林抗血小板治疗。治疗组在此基础上加用氯吡格雷:首剂给予负荷量300mg,之后75mg,一日一次口服。治疗期间观察患者临床症状、体征、心电图及药物主要不良反应等,比较两组临床疗效。结果治疗组总有效率90.48%,明显高于对照组65.00%(P<0.05),两组均无严重或危及生命的出血及并发症。结论阿司匹林联合氯吡格雷可明显改善不稳定型心绞痛患者的症状及预后,且安全性高。

作者朱剑锋李原玲吴海林杨吉栓

机构地区山西省方山县人民医院

出处《中西医结合心脑血管病杂志》 2012年第7期871-872,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

关键词阿司匹林氯吡格雷不稳定型心绞痛

分类号 R541.4 [医药卫生—心血管疾病] R256.2 [医药卫生—中医内科学]

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